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Number of results

Journal

2013 | 8 | 4 | 476-484

Article title

Wear debris from hip prostheses characterized by electron imaging

Content

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Languages of publication

EN

Abstracts

EN
The characterization of wear particles is of great importance in understanding the mechanisms of osteolysis. In this unique study, thirty-one tissue samples were retrieved at revision surgeries of hip implants and divided into four groups according to the composition of metal prosthetic components. Tissue samples were first analyzed histologically and then by scanning electron microscopy (SEM) combined with back-scattered electron imaging and energy dispersive X-ray spectroscopy. Therefore, particles were studied directly in situ in tissue sections, without the requirement for particle isolation. The composition of metal wear particles detected in the tissue sections corresponded to the composition of the implant components. A considerable number of large metal particles were actually clusters of submicron particles. The clustering of submicron particles was observed primarily with CoCrMo (cobalt-chromiummolybdenum) and, to a lesser extent, for stainless steel particles. SEM secondary and back-scattered electron imaging was an appropriate and selective method for recognizing the composition of metal particles in the in situ tissue sections, without destroying their spatial relationship within the histology. This method can be used as a screening tool for composition of metal and ceramic particles in tissue sections, or as an additional method for particle identification.

Publisher

Journal

Year

Volume

8

Issue

4

Pages

476-484

Physical description

Dates

published
1 - 8 - 2013
online
12 - 6 - 2013

Contributors

  • Valdoltra Orthopaedic Hospital, Jadranska c. 31, 6280, Ankaran, Slovenia
author
author

References

  • [1] Revell PA. The combined role of wear particles, macrophages and lymphocytes in the loosening of total joint prostheses. J. R. Soc. Interface, 2008, 5, 1263–1278 http://dx.doi.org/10.1098/rsif.2008.0142[Crossref][WoS]
  • [2] Keegan GM, Learmonth ID, Case CP. Orthopaedic metals and their potential toxicity in the arthroplasty patient: A review of current knowledge and future strategies. J. Bone Joint Surg. Br., 2007, 89, 567–573 [Crossref][WoS]
  • [3] Willert HG, Bertram H, Buchhorn GH. Osteolysis in alloarthroplasty of the hip. The role of ultra-high molecular weight polyethylene wear particles. Clin. Orthop. Relat. Res., 1990, 258, 95–107
  • [4] Essner A, Sutton K, Wang A. Hip simulator wear comparison of metal-on-metal, ceramic-on-ceramic and crosslinked UHMWPE bearings. Wear, 2005, 259, 992–995 http://dx.doi.org/10.1016/j.wear.2005.02.104[Crossref]
  • [5] Slonaker M, Goswami T. Review of wear mechanisms in hip implants: Paper II - ceramics IG004712. Materials & Design, 2004, 25, 395–405 http://dx.doi.org/10.1016/j.matdes.2003.11.011[Crossref]
  • [6] Milosev I, Trebse R, Kovac S, Cör A, Pisot V. Survivorship and retrieval analysis of Sikomet metalon-metal total hip replacements at a mean of seven years. J. Bone Joint Surg. Am., 2006, 88, 1173–1182 http://dx.doi.org/10.2106/JBJS.E.00604[Crossref]
  • [7] Yoon TR, Rowe SM, Jung ST, Seon KJ, Maloney WJ. Osteolysis in association with a total hip arthroplasty with ceramic bearing surfaces. J. Bone Joint Surg. Am., 1998, 80-A, 1459–1467
  • [8] Jin Z, Fisher J. Tribology in joint replacement. In: Revel PA (Ed.), Joint replacement technology. Cambridge, Woodhead Publishing Ltd, 2008, 31–55 http://dx.doi.org/10.1533/9781845694807.1.31[Crossref]
  • [9] Firkins P J, Tipper JL, Saadatzadeh MR, Ingham E, Stone MH, Farrar R, Fisher J. Quantitative analysis of wear and wear debris from metal-on-metal hip prostheses tested in a physiological hip joint simulator. Biomed. Mater. Eng., 2001, 11, 143–157
  • [10] Papageorgiou I, Brown C, Schins R, Newson R, Davis S, Fisher J, Ingham E, Case CP. The effect of nano- and micron-sized particles of cobalt-chromium alloy on human fibroblasts in vitro. Biomaterials, 2007, 28, 2946–2958 http://dx.doi.org/10.1016/j.biomaterials.2007.02.034[Crossref][WoS]
  • [11] Germain MA, Hatton A, Williams S, Matthews JB, Stone MH, Fisher J, Ingham E. Comparison of the cytotoxicity of clinically relevant cobalt-chromium and alumina ceramic wear particles in vitro. Biomaterials, 2003, 24, 469–479 http://dx.doi.org/10.1016/S0142-9612(02)00360-5[Crossref]
  • [12] Shea KG, Lundeen GA, Bloebaum RD, Bachus KN, Zou L. Lymphoreticular dissemination of metal particles after primary joint replacements. Clin. Orthop. Relat. Res., 1997, 338, 219–326 http://dx.doi.org/10.1097/00003086-199705000-00029[Crossref]
  • [13] Milosev I, Pisot V, Campbell P. Serum levels of cobalt and chromium in patients with Sikomet metal-metal total hip replacements. J. Orthop. Res., 2005, 23, 526–535 http://dx.doi.org/10.1016/j.orthres.2004.12.007[Crossref]
  • [14] Catelas I, Campbell PA, Bobyn JD, Medley JB, Huk OL. Wear particles from metal-on-metal total hip replacements: effects of implant design and implantation time. Proc. Inst. Mech. Eng. H, 2006, 220, 195–208 [Crossref]
  • [15] Goodman SB. Wear particles, periprosthetic osteolysis and the immune system. Biomaterials, 2007, 28, 5044–5048 http://dx.doi.org/10.1016/j.biomaterials.2007.06.035[WoS][Crossref]
  • [16] Robinson VNE. Materials characterization using the backscattered electron signal in scanning electron microscopy. Scanning Microscopy, 1987, 1, 107–117
  • [17] Sabokbar A, Pandey R, Athanasou NA. The effect of particle size and electrical charge on macrophage-osteoclast differentiation and bone resorption. J. Mater. Sci. Mater. Med., 2003, 14, 731–738. http://dx.doi.org/10.1023/A:1025088418878[Crossref]
  • [18] Catelas I, Bobyn JD, Medley JB, Krygier JJ, Zukor DJ, Petit A, Huk OL. Effects of digestion protocols on the isolation and characterization of metalmetal wear particles. I. Analysis of particle size and shape. J. Biomed. Mater. Res., 2001, 55, 320–329 http://dx.doi.org/10.1002/1097-4636(20010605)55:3<320::AID-JBM1020>3.0.CO;2-3[Crossref]
  • [19] Margevicius KJ, Bauer TW, McMahon JT, Brown SA, Merritt K. Isolation and characterization of debris in membranes around total joint prostheses. J. Bone Joint Surg. Am., 1994, 76, 1664–1675
  • [20] Catelas I, Medley JB, Campbell PA, Huk OL, Bobyn JD. Comparison of in vitro with in vivo characteristics of wear particles from metal-metal hip implants. J. Biomed. Mater. Res. B. Appl. Biomater., 2004, 70, 167–178 http://dx.doi.org/10.1002/jbm.b.20036[Crossref]
  • [21] Doorn PF, Campbell PA, Worrall J, Benya PD, McKellop HA, Amstutz HC. Metal wear particle characterization from metal on metal total hip replacements: transmission electron microscopy study of periprosthetic tissues and isolated particles. J. Biomed. Mater. Res., 1998, 42, 103–111 http://dx.doi.org/10.1002/(SICI)1097-4636(199810)42:1<103::AID-JBM13>3.0.CO;2-M[Crossref]
  • [22] Milosev I, Remskar M. In vivo production of nanosized metal wear debris formed by tribochemical reaction as confirmed by high-resolution TEM and XPS analyses. J. Biomed. Mater. Res. A, 2009, 91, 1100–1110 [WoS][Crossref]
  • [23] Lerouge S, Huk O, Yahia LH, Sedel L. Characterization of in vivo wear debris from ceramic-ceramic total hip arthroplasties. J. Biomed. Mater. Res., 1996, 32, 627–633 http://dx.doi.org/10.1002/(SICI)1097-4636(199612)32:4<627::AID-JBM16>3.0.CO;2-A[Crossref]
  • [24] Doorn PF, Mirra JM, Campbell PA, Amstutz HC. Tissue reaction to metal on metal total hip prostheses. Clin. Orthop. Relat. Res., 1996, 329S, 187–205 http://dx.doi.org/10.1097/00003086-199608001-00017[Crossref]
  • [25] Bloebaum RD, Bachus KD, Boyce TM. Backscattered electron imaging: the role in calcified tissue and implant analysis. J. Biomater. Appl., 1990, 5, 56–85
  • [26] Shanbhag AS, Jacobs JJ, Glant TT, Gilbert JL, Black J, Galante JO. Composition and morphology of wear debris in failed uncemented total hip replacement. J. Bone Joint Surg. Br., 1994, 76, 60–67
  • [27] Daley B, Doherty AT, Fairman B, Case CP. Wear debris from hip or knee replacements causes chromosomal damage in human cells in tissue culture. J. Bone Joint Surg. Br., 2004, 86, 598–606
  • [28] Stachowiak GW, Stachowiak GB, Campbell P. Application of numerical descriptors to the characterization of wear particles obtained from joint replacements. Proc. Inst. Mech. Eng. H, 1997, 211, 1–10
  • [29] Tipper JL, Firkins PJ, Besong AA, Barbour PSM, Nevelos J, Stone MH, Ingham E, Fisher J. Characterisation of wear debris from UHMWPE on zirconia ceramic, metal-on-metal and alumina ceramic-on-ceramic hip prostheses generated in a physiological anatomical hip joint simulator. Wear, 2001, 250, 120–128 http://dx.doi.org/10.1016/S0043-1648(01)00653-6[Crossref]
  • [30] Shahgaldi BF, Heatley FW, Dewar A, Corrin B. In vivo corrosion of cobalt-chromium and titanium wear particles. J. Bone Joint Surg. Br., 1995, 77, 962–966
  • [31] Walker PS, Gold BL. The tribology (friction, lubrication and wear) of all-metal artificial hip joints. Clin. Orthop. Relat. Res., 1996, 329Suppl, 4–10 http://dx.doi.org/10.1097/00003086-199608001-00002[Crossref]
  • [32] Maloney WJ, Smith RL, Schmalzried TP, Chiba J, Huene D, Rubash H. Isolation and characterization of wear particles generated in patients who have had failure of a hip arthroplasty without cement. J. Bone Joint Surg. Am., 1995, 77, 1301–1310
  • [33] Jacobs JJ, Skipor AK, Black J, Urban R, Galante JO. Release and excretion of metal in patients who have a total hip-replacement component made of titanium-base alloy. J. Bone Joint Surg. Am., 1991, 73, 1475–1486

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-013-0156-7
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