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2013 | 8 | 4 | 377-382
Article title

Chemical robotics - chemotactic drug carriers

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Abstracts
EN
In this review we show and describe a concept of designing autonomously moving artificial cells (chemical robots) carrying drugs and having tactic behavior based on artificial chemotaxis. Such systems could help to provide new and more efficient drug delivery applications. Chemical robot can be constructed based on the self-organization - natural “bottom-up” way - of fatty acid or lipid molecules into ordered nano- or micrometer size objects that have the ability to move and respond to environmental stimuli. The idea of using tactic carriers in drug delivery applications can be justified by the fact that cancer sites in the living body have different physiological characters (lower pH and higher resting temperature) compared to normal cells. The proposed “bottom-up” design method for self-propelled objects at small scales for targeted drug delivery applications could realize the original designation of nanoscience proposed 50 years ago by Richard Feynman.
Publisher

Journal
Year
Volume
8
Issue
4
Pages
377-382
Physical description
Dates
published
1 - 8 - 2013
online
12 - 6 - 2013
Contributors
author
  • Department of Physics, Budapest University of Technology and Economics, H-1111, Budapest, Budafoki út 8, Hungary, lagzi@vuk.chem.elte.hu
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Document Type
Publication order reference
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YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-012-0130-9
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