Chronic Idiopathic Thrombocytopenic Purpura in children: predictive factors and outcome

• Authors: Paola Coccia , Antonio Ruggiero , Giorgio Attinà , Giuseppe Cerchiara , Andrea Battista , Roberta Arena , Maria Scalzone , Nadia Puma , Vita Ridola , Riccardo Riccardi
• Languages of publication: EN

Abstracts

EN

Idiopathic thrombocytopenic purpura (ITP) is the most common cause of acquired thrombocytopenia in children. In 20% of cases, this condition is classified as chronic when the thrombocytopenia is persistent 6 months after diagnosis. The aim of the present study is to identify the potential factors correlating with a favorable outcome in patients with chronic ITP. Some 71 patients affected by ITP were retrospectively analyzed. Results show a higher rate of spontaneous recovery that is statistically significant for patients with platelet count at diagnosis <20,000/µL. These observations suggest the possibility to delay or avoid aggressive surgical treatment for these patients.

Keywords

EN

Idiopathic thrombocytopenic purpura; Spontaneous remission; Prognosis; Children

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2012
• Volume: 7
• Issue: 4
• Pages: 525-528

Dates

published

1 - 8 - 2012

online

24 - 5 - 2012

Contributors

author

Paola Coccia

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Antonio Ruggiero

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Giorgio Attinà

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Giuseppe Cerchiara

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Andrea Battista

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Roberta Arena

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Maria Scalzone

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Nadia Puma

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Vita Ridola

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

author

Riccardo Riccardi

• Division of Pediatric Oncology, Catholic University, Largo A. Gemelli 8, 00168, Roma, Italy

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Identifiers

DOI

10.2478/s11536-012-0011-2