Skipping breakfast is correlated with impaired fasting glucose in apparently healthy subjects

• Authors: Natalia Voronova , Alexey Nikitin , Alexander Chistiakov , Dimitry Chistiakov
• Languages of publication: EN

Abstracts

EN

Regular food consumption plays a critical role in normal glucose homeostasis. Today, a few studies have evaluated the level of fasting glucose in individuals who skip breakfast, which should theoretically lead to a lack of supplementary energy and thereby increase the risk for subsequent hypoglycemia. The prevalence of suspected habitual skipping breakfast (SHSB) (at least three times weekly) was evaluated with a simple question, along with measurement of fasting plasma glucose level and assessment of cardiovascular and lifestyle risk factors in a cross-sectional study of 2,331 asymptomatic adults who had never been treated with insulin or oral anti-diabetic drugs. The overall prevalence of SHSB was 16.3% (20.1% for men and 9.4% for women, P<0.0001, χ2-test). Compared with a normal fasting glucose level, an impaired fasting glucose (IFG) level (100–125 mg/dl), but not high fasting glucose (≥126 mg/dl), was significantly associated with SHSB, and this association remained after adjustment for relevant confounders [odds ratio (95% CI): 1.75 (1.33–2.30) and 2.10 (0.93–4.71), respectively]. Age (inversely), current smoker, late dinner just before sleeping, infrequent exercise, and high C-reactive protein (≥1.8 mg/L) were independently associated with SHSB. In a subgroup of subjects who underwent a 75g-oral glucose tolerance test (n = 1,315), isolated IFG (n = 272) was solely significantly associated with SHSB. Our results suggest that IFG, subtle inflammatory state, and high-risk lifestyle factors for diabetes and cardiovascular disease may have an association in asymptomatic adults who habitually skip breakfast.

Keywords

EN

Visceral leishmaniasis; Liposomal amphotericin B; Renal function; Uric acid; Tumor lysis syndrome

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2012
• Volume: 7
• Issue: 3
• Pages: 376-382

Dates

published

1 - 6 - 2012

online

29 - 3 - 2012

Contributors

author

Natalia Voronova

• Endocrinology Research Center, Ulitsa Dm. Ul’yanova 11, 117036, Moscow, Russia

author

Alexey Nikitin

• Department of Molecular Diagnostics, National Research Center GosNIIgenetika, 1st Dorozhny Proezd 1, 117545, Moscow, Russia

author

Alexander Chistiakov

• Endocrinology Research Center, Ulitsa Dm. Ul’yanova 11, 117036, Moscow, Russia

author

Dimitry Chistiakov

• Department of Medical Nanobiotechnology, Pirogov Russian State Medical University, Ulitsa Ostrovityanova 1, 117997, Moscow, Russia

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Identifiers

DOI

10.2478/s11536-011-0150-x