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2012 | 7 | 1 | 91-94

Article title

Double-trouble: An unusual case of two simultaneous arterial thromboses in thrombophilia


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Multiple arterial and venous thromboses are usually related to thrombophilia or antiphospholipid syndrome. Recurrent pulmonary embolism strongly indicates the presence of genetic or acquired thrombophilic factors. Simultaneous double arterial in situ thromboses are unusual, even in thrombophilic conditions. Simultaneous occurrence of pulmonary embolism and cerebrovascular ischaemic insult are highly indicative of existence of patent foramen ovale. We present herein a patient with the double simultaneous arterial thromboses as the manifestation of thrombophilia (heterozygous for methylenetetrahydrofolate-reductase (MTHFR) C677T gene mutation). There was no patent foramen ovale suspected upon the patient’s admittance to hospital. To the best of our knowledge there have been no similar cases presented to date.










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1 - 2 - 2012
24 - 11 - 2011


  • Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia
  • Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia
  • Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000, Belgrade, Serbia


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  • [6] Dixon T., Panda M., Desbiens N. The simultaneous occurrence of deep vein thrombosis and pulmonary and arterial embolization. J Gen Intern Med., 2007, 22, 1040–1041 http://dx.doi.org/10.1007/s11606-007-0169-5[Crossref][WoS]
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