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Journal

2011 | 6 | 6 | 727-731

Article title

Q-fever presenting as an autoimmune disease: case report and review

Content

Title variants

Languages of publication

EN

Abstracts

EN
Q fever is a worldwide zoonosis caused by the intracellular bacterium Coxiella burnetti. Autoimmune phenomena associated with the disease may obscure the clinical picture, and in many reports mislead physicians to an initial diagnosis of an autoimmune disease. We present a case of chronic Q-fever, complicated by myocarditis/pericarditis, where patient’s initial signs, symptoms and laboratory findings (i.e., protracted fever, oligoarthritis, erythema nodosum, positive antineutrophil cytoplasmic antibodies, monoclonal gammopathy) seemed to suggest an autoimmune disease. We also review the literature for autoimmune phenomena associated with Q-fever.

Publisher

Journal

Year

Volume

6

Issue

6

Pages

727-731

Physical description

Dates

published
1 - 12 - 2011
online
8 - 10 - 2011

Contributors

  • Department of Pathophysiology, Laikon General Hospital and Medical School, National and Kapodistrian University of Athens, Athens, 11527, Greece
  • Laboratory of Clinical Bacteriology, Parasitology, Zoonoses and Geographic Medicine, WHO Collaborating Center for Mediterranean Zoonoses, University of Crete, Heraklion, 71110, Crete, Greece
  • Department of Pathophysiology, Laikon General Hospital and Medical School, National and Kapodistrian University of Athens, Athens, 11527, Greece

References

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  • [2] Tissot-Dupont H., Raoult D., Q fever, Infect. Dis. Clin. North. Am., 2008, 22, 505–514 http://dx.doi.org/10.1016/j.idc.2008.03.002[Crossref]
  • [3] Tissot-Dupont H., Raoult D., Brouqui P., Janbon F., Peyramond D., Weiller P.J., et al., Epidemiologic features and clinical presentation of acute Q fever in hospitalized patients: 323 French cases, Am. J. Med., 1992, 93, 427–434 http://dx.doi.org/10.1016/0002-9343(92)90173-9[Crossref]
  • [4] Raoult D., Marrie T., Mege J., Natural history and pathophysiology of Q fever, Lancet Infect. Dis., 2005, 5, 219–226 http://dx.doi.org/10.1016/S1473-3099(05)70052-9[Crossref]
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  • [9] Lefebvre M., Grossi O., Agard C., Perret C., Le Pape P., Raoult D., et al., Systemic immune presentations of Coxiella burnetii infection (Q Fever), Semin. Arthritis Rheum., 2010, 39, 405–409 http://dx.doi.org/10.1016/j.semarthrit.2008.10.004[WoS][Crossref]
  • [10] Swaby E.D., Fisher-Hoch S., Lambert H.P., Stern H., Is Kawasaki disease a variant of Q fever? Lancet, 1980, 2, 146 http://dx.doi.org/10.1016/S0140-6736(80)90026-4[Crossref]
  • [11] Torley H., Capell H., Timbury M., McCartney C., Chronic Q fever with mixed cryoglobulinemia, Ann. Rheum. Dis., 1989, 48, 254–255 http://dx.doi.org/10.1136/ard.48.3.254[Crossref]
  • [12] Odeh M., Oliven A., Temporal arteritis associated with Q fever. A case report, Angiology, 1994, 45, 1053–1057 http://dx.doi.org/10.1177/000331979404501209[Crossref]
  • [13] Conget I., Mallolas J., Mensa J., Rovira M., Erythema nodosum and Q fever, Arch. Dermatol., 1987, 123, 867 http://dx.doi.org/10.1001/archderm.123.7.867b[Crossref]
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  • [16] Wong R.C., Wilson R., Silcock R., Kratzing L.M., Looke D., Unusual combination of positive IgG autoantibodies in acute Q-fever infection, Intern. Med. J., 2001, 31, 432–435 http://dx.doi.org/10.1046/j.1445-5994.2001.00099.x[Crossref]
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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-011-0097-y
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