Complete remission of primary bilateral adrenal lymphoma achieved by Rituximab-CHOP chemotherapy

• Authors: Yin-long Yang , Ting-ting Ye , Zhu-yin Wang , Er-li Gao , Lei-ping Wang , Peng Li , Xue-min Chen , Xiao-hua Zhang
• Languages of publication: EN

Abstracts

EN

Primary adrenal lymphoma (PAL) is an exceedingly rare disease. Because of its rareness, uncertain etiology, variable duration of survival, unremarkable clinical presentations and unsatisfied therapeutic strategies, its treatment has always been unsatisfactory. Here we report a 50-year-old male patient with primary bilateral adrenal diffuse large B-cell lymphoma. He was treated with surgery followed by combined chemotherapy using R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). He achieved complete remission after 3 cycles of chemotherapy. At present, he is considered free of tumor at 3 years after chemotherapy. Our case report demonstrates that patients with primary bilateral adrenal diffuse large B-cell lymphoma may achieve a good outcome using R-CHOP chemotherapy. To the best of our knowledge, our patient who achieved complete remission after R-CHOP chemotherapy has had the longest survival as published in the literature.

Keywords

EN

Primary adrenal lymphoma; Non-Hodgkin lymphoma; R-CHOP; Complete Remission

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2011
• Volume: 6
• Issue: 6
• Pages: 778-782

Dates

published

1 - 12 - 2011

online

8 - 10 - 2011

Contributors

author

Yin-long Yang

• Department of Oncology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

author

Ting-ting Ye

• Department of Endocrinology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

author

Zhu-yin Wang

• Department of Medicine, The First Clinical Medical Institute of Wenzhou Medical College, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

author

Er-li Gao

• Department of Oncology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

author

Lei-ping Wang

• Department of Medical Oncology, Cancer Hospital, Fudan University, Shanghai, 200000, China

author

Peng Li

• Department of Pathology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

author

Xue-min Chen

• Department of Oncology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

author

Xiao-hua Zhang

• Department of Oncology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, Zhejiang Province, China

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Identifiers

DOI

10.2478/s11536-011-0090-5