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Journal
2011 | 6 | 5 | 631-633
Article title

Sudden onset blindness treated with pulse steroid therapy in a patient with microscopic polyangiitis

Content
Title variants
Languages of publication
EN
Abstracts
EN
We report a 71-year-old male with microscopic polyangiitis (MPA) who developed sudden-onset, progressive, bilateral visual loss associated with a relapse of MPA symptoms. The patient was referred to our hospital, and treated with intravenous pulse steroid therapy and high-dose oral prednisolone. Although the right eye remained vision deficient, visual acuity in the left eye recovered. Ocular manifestations of MPA are quite uncommon. This case emphasizes the necessity of early detection and initiation of prompt therapy where ocular manifestations of MPA occur.
Publisher

Journal
Year
Volume
6
Issue
5
Pages
631-633
Physical description
Dates
published
1 - 10 - 2011
online
9 - 8 - 2011
Contributors
author
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan, yoshirohorai0518@qmed.hosp.go.jp
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan
author
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan
author
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan
  • Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8-1 Jigyohama Chuo-ku, Fukuoka, 810-8563, Japan
References
  • [1] Rarok AA, Limburg PC, Kallenberg CG. Neutrophilactivating potential of antineutrophil cytoplasm autoantibodies. J Leukoc Biol, 2003, 7, 3–15 http://dx.doi.org/10.1189/jlb.1202611[Crossref]
  • [2] Guillevin L, Durand-Gasselin B, Cevallos R, et al. Microscopic polyangiitis: clinical and laboratory findings in eighty-five patients. Arthritis Rheum, 1999, 42, 421–430 http://dx.doi.org/10.1002/1529-0131(199904)42:3<421::AID-ANR5>3.0.CO;2-6[Crossref]
  • [3] Yoshida M. Clinical analysis of anti-neutrophil cytoplasmic antibody in diagnosis of collagen diseases. Nippon Naika Gakkai Zasshi(Japanese). 2003, 92, 1941–1947 http://dx.doi.org/10.2169/naika.92.1941[Crossref]
  • [4] Tamura N, Matsudaira R, Hirashima M, et al. Two cases of refractory Wegener’s granulomatosis successfully treated with rituximab. Intern Med, 2007, 46:409–414 http://dx.doi.org/10.2169/internalmedicine.46.6156[WoS][Crossref]
  • [5] Duran E, Merkel PA, Sweet S, Swan N, Babikian VL. ANCA-associated small vessel vasculitis presenting with ischemic optic neuropathy. Neurology, 2004, 62, 152–153 [PubMed]
  • [6] Altaie R, Ditizio F, Fahy GT. Microscopic polyangitis presenting with sub-acute reversible optic neuropathy. Eye, 2004, 19, 363–365 http://dx.doi.org/10.1038/sj.eye.6701479[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-011-0069-2
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