Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results

Journal

2011 | 6 | 4 | 442-448

Article title

HLA-Cw and TCR vβ analysis in twenty Mexican patients with psoriasis

Content

Title variants

Languages of publication

EN

Abstracts

EN
Genetic background and T-cell expansion have been confirmed as the most important factors leading to psoriasis susceptibility in the Caucasian population. This study was performed to identify the T-cell receptor Vβ repertoire and HLA-Cw genotype in twenty Mexicans of two different ethnicities with severe chronic plaque-type psoriasis. HLA-Cw typing was performed to detect the allele pattern by SSP-PCR. In parallel, RT-PCR and Western blot were used for the identification of the TCR Vβ expression in peripheral blood cells. We identified a variety of HLA-Cw alleles in this group of patients distinct from the widely known HLA-Cw 0602 Caucasian allele. Moreover, TCR Vβ-2 and Vβ-7 clone-type frequencies were different and statistically significant (P = 0.0280). We speculate that because of diverse genetic backgrounds, the susceptibility to disease and activation of T-cells for a proper immune response could be specific; therefore, the findings might contribute to the elucidation of the pathogenesis in psoriatic Mexican patients.

Publisher

Journal

Year

Volume

6

Issue

4

Pages

442-448

Physical description

Dates

published
1 - 8 - 2011
online
1 - 6 - 2011

Contributors

  • Division of Molecular Biology, Institute for Scientific and Technological Research of San Luis Potosi (IPICYT), A.C., 78216, San Luis Potosi, Mexico
  • Division of Molecular Biology, Institute for Scientific and Technological Research of San Luis Potosi (IPICYT), A.C., 78216, San Luis Potosi, Mexico
  • Departmento de Dermatología, Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico
  • Division of Molecular Biology, Institute for Scientific and Technological Research of San Luis Potosi (IPICYT), A.C., 78216, San Luis Potosi, Mexico
  • Division of Molecular Biology, Institute for Scientific and Technological Research of San Luis Potosi (IPICYT), A.C., 78216, San Luis Potosi, Mexico
author
  • Division of Molecular Biology, Institute for Scientific and Technological Research of San Luis Potosi (IPICYT), A.C., 78216, San Luis Potosi, Mexico
  • Departmento de Microbiología, Centro de Ciencias Basicas, Universidad Autonoma de Aguascalientes, Aguascalientes, Mexico
  • Departmento de Dermatología, Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico
  • Departmento de Dermatología, Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico

References

  • [1] Nevitt, G.J., Hutchinson, P.E., Br J Dermatol 1996, 135, 533–537 http://dx.doi.org/10.1111/j.1365-2133.1996.tb03826.x[Crossref]
  • [2] Raychaudhuri, S.P., Farber, E.M., J Eur Acad Dermatol Venereol 2001, 15, 16–17 http://dx.doi.org/10.1046/j.1468-3083.2001.00192.x[Crossref]
  • [3] Chang, Y.T., Liu, H.N., Shiao, Y.M., Lin, M.W., Lee, D.D., Liu, M.T., Wang, W.J., Wu, S., Lai, C.Y., Tsai, S.F., Br J Dermatol 2005, 153, 90–96; Yan, L.N., Li, S.Y., Dong, Z., Dong, L., Xie, J.H., An, S.P., Yuan, Y.H., Tissue Antigens 2008, 72, 409–410 http://dx.doi.org/10.1111/j.1365-2133.2005.06570.x[Crossref]
  • [4] Holm, S.J., Sanchez, F., Carlen, L.M., Mallbris, L., Stahle, M., O’Brien, K.P., Acta Derm Venereol 2005, 85, 2–8 http://dx.doi.org/10.1080/00015550410023527[Crossref]
  • [5] Dobosz, A.S., Rebaa, K., Szczerkowska, Z., Nedoszytko, B., International Journal of Immunogenetics 2005, 32, 389–391 http://dx.doi.org/10.1111/j.1744-313X.2005.00543.x[Crossref]
  • [6] Higgins, C.M., Lund, T., Shipley, M.E., Ebringer, A., Sadowska-Wroblewska, M., Craig, R.K., Ann Rheum Dis 1992, 51, 855–862 http://dx.doi.org/10.1136/ard.51.7.855[Crossref]
  • [7] Kramer, A.B., Roozendaal, C., Dullaart, R.P., Thyroid 2004, 14, 544–547 http://dx.doi.org/10.1089/1050725041517048[Crossref]
  • [8] Nair, R.P., Stuart, P.E., Nistor, I., Hiremagalore, R., Chia, N.V., Jenisch, S., Weichenthal, M., Abecasis, G.R., Lim, H.W., Christophers, E., Voorhees, J.J., Elder, J.T., Am J Hum Genet 2006, 78, 827–851 http://dx.doi.org/10.1086/503821[Crossref]
  • [9] Nickoloff, B.J., Nestle, F.O., J Clin Invest 2004, 113, 1664–1675
  • [10] Bour, H., Puisieux, I., Even, J., Kourilsky, P., Favrot, M., Musette, P., Nicolas, J.F., Hum Immunol 1999, 60, 665–676 http://dx.doi.org/10.1016/S0198-8859(99)00027-0[Crossref]
  • [11] Chang, J.C., Smith, L.R., Froning, K.J., Schwabe, B.J., Laxer, J.A., Caralli, L.L., Kurland, H.H., Karasek, M.A., Wilkinson, D.I., Carlo, D.J., et al., Proc Natl Acad Sci U S A 1994, 91, 9282–9286 http://dx.doi.org/10.1073/pnas.91.20.9282[Crossref]
  • [12] Hwang, H.Y., Bahk, Y.Y., Kim, T.G., Kim, T.Y., J Invest Dermatol 2003, 120, 359–364 http://dx.doi.org/10.1046/j.1523-1747.2003.12055.x[Crossref]
  • [13] Vollmer, S., Menssen, A., Prinz, J.C., J Invest Dermatol 2001, 117, 1296–1301 http://dx.doi.org/10.1046/j.0022-202x.2001.01494.x[Crossref]
  • [14] Fernandes, S., Chavan, S., Chitnis, V., Kohn, N., Pahwa, S., Clin Diagn Lab Immunol 2005, 12, 477–483
  • [15] Gorodezky C, A.C., Vázquez-García MN, de la Rosa G, Infante E, Balladares S, Toribio R, Pérez-Luque E, Muñoz L., Human Immunology 2001, 62, 979–991 http://dx.doi.org/10.1016/S0198-8859(01)00296-8[Crossref]
  • [16] Fan, X., Yang, S., Huang, W., Wang, Z.M., Sun, L.D., Liang, Y.H., Gao, M., Ren, Y.Q., Zhang, K.Y., Du, W.H., Shen, Y.J., Liu, J.J., Zhang, X.J., PLoS Genet 2008, 4, e1000038; Fan, X., Yang, S., Sun, L.D., Liang, Y.H., Gao, M., Zhang, K.Y., Huang, W., Zhang, X., Acta Derm Venereol 2007, 87, 335–340
  • [17] Orru, S., Giuressi, E., Carcassi, C., Casula, M., Contu, L., Am J Hum Genet 2005, 76, 164–171; Scola, L., Lio, D., Candore, G., Forte, G.I., Crivello, A., Colonna-Romano, G., Pes, M.G., Carru, C., Ferrucci, L., Deiana, L., Baggio, G., Franceschi, C., Caruso, C., Exp Gerontol 2008, 43, 114–118; Lio, D., Pes, G.M., Carru, C., Listi, F., Ferlazzo, V., Candore, G., Colonna-Romano, G., Ferrucci, L., Deiana, L., Baggio, G., Franceschi, C., Caruso, C., Exp Gerontol 2003, 38, 313–317 http://dx.doi.org/10.1086/426948[Crossref]
  • [18] Kay, R.A., Hutchings, C.J., Ollier, W.E., Hum Immunol 1995, 42, 328–330; Menssen, A., Vollmer, S., Trommler, P., Sander, C., Prinz, J.C., J Invest Dermatol 2000, 115, 66–73; Yoshioka, T., Matsutani, T., Iwagami, S., Toyosaki-Maeda, T., Yutsudo, T., Tsuruta, Y., Suzuki, H., Uemura, S., Takeuchi, T., Koike, M., Suzuki, R., Immunology 1999, 96, 465–472 http://dx.doi.org/10.1016/0198-8859(94)00115-7[Crossref]
  • [19] Dokouhaki, P., Moghadam, R., Akbariasbagh, F., Zarnani, A., Novin, M.G., Razavi, A., Jeddi-Tehrani, M., Am J Reprod Immunol 2006, 55, 349–359; Hodges, E., Dasmahapatra, J., Smith, J.L., Quin, C.T., Lanham, S., Krishna, M.T., Holgate, S.T., Frew, A.J., Clin Exp Immunol 1998, 112, 363–374 http://dx.doi.org/10.1111/j.1600-0897.2006.00375.x[Crossref]
  • [20] Carlen, L., Sakuraba, K., Stahle, M., Sanchez, F., J Invest Dermatol 2007, 127, 342–348; Komatsu, T., Moriya, N., Shiohara, T., Clin Exp Immunol 1996, 104, 343–350 http://dx.doi.org/10.1038/sj.jid.5700549[Crossref]
  • [21] Ahangari, G., Halapi, E., Tehrani, M.J., Fransson, J., Hammar, H., Wigzell, H., Scand J Immunol 1997, 45, 534–540 http://dx.doi.org/10.1046/j.1365-3083.1997.d01-422.x[Crossref]
  • [22] Diluvio, L., Vollmer, S., Besgen, P., Ellwart, J.W., Chimenti, S., Prinz, J.C., J Immunol 2006, 176, 7104–7111
  • [23] Kansal, R.G., Nizet, V., Jeng, A., Chuang, W.J., Kotb, M., J Infect Dis 2003, 187, 398–407 http://dx.doi.org/10.1086/368022[Crossref]

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-011-0038-9
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.