Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results

Journal

2011 | 6 | 1 | 49-57

Article title

Preconceptional screening of sexually transmitted infections/diseases

Content

Title variants

Languages of publication

EN

Abstracts

EN
Hungarian Preconceptional Care includes the preconceptional screening of sexually transmitted infections/disorders (STD) and vaginal candidosis of potential mothers and pyospermia of potential fathers. The aim of this study was to evaluate the effect of this screening and treatment for the rate of preterm births. Clinical and subclinical vaginal candidiasis (asymptomatic candida colonisation), combination of STD and vaginal candidiasis, STD without vaginal candidiasis, finally women without STD and vaginal candidiasis as references were evaluated in 4,672 pregnant women. The association of STD in pregnant women with higher risk of preterm birth was confirmed. However, an association was also found between clinically diagnosed vaginal candidiasis, asymptomatic candida colonisation, and a higher risk for preterm births. This risk was reduced with clotrimazole treatment. However, pregnant women without recognized STD and/or vaginal candidiasis had a higher risk for preterm birth than pregnant women with STD or vaginal candidiasis after appropriate treatment. Thus the conclusion of the study is that the preconceptional screening of STD and vaginal candidiasis followed by appropriate treatment is important to prevent a certain part of preterm birth but it is necessary to improve the efficacy of the previously used methods for this screening.

Publisher

Journal

Year

Volume

6

Issue

1

Pages

49-57

Physical description

Dates

published
1 - 2 - 2011
online
16 - 12 - 2010

Contributors

  • Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, 1082, Budapest, Hungary
author
  • Family Planning Clinic, Foundation for the Community Control of Hereditary Diseases, 1148, Budapest, Hungary
  • Family Planning Clinic, Foundation for the Community Control of Hereditary Diseases, 1148, Budapest, Hungary

References

  • [1] Czeizel AE, Dobo M, Dudas I et al.: The Hungarian Periconceptional Service as a model for community genetics. Community Genetics 1998, 1, 252–259 http://dx.doi.org/10.1159/000016171[Crossref]
  • [2] Czeizel AE: Ten years’ experience in periconception care. Eur J Obstet Gynecol Reprod Biol 1999, 84, 43–49 http://dx.doi.org/10.1016/S0301-2115(98)00246-2[Crossref]
  • [3] Czeizel AE: Periconceptional Care: An experiment in community genetics. Community Genetics 2000, 3, 119–123 http://dx.doi.org/10.1159/000051120[Crossref]
  • [4] Czeizel AE, Dudás I: Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med 1992, 328, 1832–1835 http://dx.doi.org/10.1056/NEJM199212243272602[Crossref]
  • [5] Czeizel AE, Dudás I, Métneki J: Pregnancy outcomes in a randomised controlled trial of periconceptional multivitamin supplementation. Final results. Arch Gynecol Obstet 1994, 255, 131–139 http://dx.doi.org/10.1007/BF02390940[Crossref]
  • [6] Czeizel AE: Prevention of congenital abnormalities by periconceptional multivitamin supplementation. Br Med J 1993, 306, 1645–1648 http://dx.doi.org/10.1136/bmj.306.6893.1645[Crossref]
  • [7] Czeizel AE: Reduction of urinary tract and cardiovascular defects by periconceptional multivitamin supplementation. Am J Med Genet 1997, 62, 179–183 http://dx.doi.org/10.1002/(SICI)1096-8628(19960315)62:2<179::AID-AJMG12>3.0.CO;2-L[Crossref]
  • [8] Czeizel AE, Dobo M, Vargha P: Hungarian cohort controlled trial of periconceptional multivitamin supplementation shows a reduction in certain congenital abnormalities. Birth Defects Res (Part A) 2004, 70, 853–861 http://dx.doi.org/10.1002/bdra.20086[Crossref]
  • [9] Czeizel AE: Periconceptional folic acid and multivitamin supplementation for the prevention of neural tube defects and other congenital abnormalities. Birth Defects Res (Part A) 2009, 85, 260–268 http://dx.doi.org/10.1002/bdra.20563[Crossref]
  • [10] Gönczy L, Czeizel AE: Integrating smoking cessation into periconception care. Tob Control 1996, 5, 160–161 http://dx.doi.org/10.1136/tc.5.2.160a[Crossref]
  • [11] Czeizel AE, Dudás I, Fritz G: The check-up of reproductive heath and genetic counseling. Genet Counsel 1992, 3, 61–66
  • [12] Hay Ph, Czeizel AE: Asymptomatic trichomonas and candida colonization and pregnancy outcome. Best Pract Res Clin Obstet Gynaecol 2007, 21, 403–409 http://dx.doi.org/10.1016/j.bpobgyn.2007.02.002[Crossref]
  • [13] Czeizel AE, Gasztonyi Z, Kuliev A: Periconception clinics: A medical healthcare infrastructure of new genetics. Fetal Diagn Ther 2005, 20, 515–518 http://dx.doi.org/10.1159/000088042[Crossref]
  • [14] WHO: WHO Laboratory Manuel for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 3rd ed. Cambridge Univ. Press, Cambridge, 1992
  • [15] Rothenberg RB, Simon R, Chipperfield E et al.: Efficacy of selected diagnostic tests for sexually transmitted diseases. JAMA 1976, 235, 49–51 http://dx.doi.org/10.1001/jama.235.1.49[Crossref]
  • [16] Spence MR, Hollander DH, Smith J et al.: The clinical and laboratory diagnosis of Trichomonas vaginal infection. Sex Transm Dis 1980, 7, 198–171
  • [17] Amsel R, Totten PA, Spiegel CA et al.: Nonspecific vaginitis: diagnostic criteria and microbial and epidemiological applications. Am J Med 1983, 74, 14–22 http://dx.doi.org/10.1016/0002-9343(83)91112-9[Crossref]
  • [18] Donders GGG, Vereecken A, Dekeersmaecker A et al.: Wet mount reflects functional vaginal lactobacillary flora better than Gram stain. J Clin Pathol 2000, 53, 308–314. http://dx.doi.org/10.1136/jcp.53.4.308[Crossref]
  • [19] Abbott J: Clinical and microscopic diagnosis of vaginal yeast infection: a prospective analysis. Ann Emerg Med 1995, 25, 587–591 http://dx.doi.org/10.1016/S0196-0644(95)70168-0[Crossref]
  • [20] Van der Schee C, van Belkum A, Zwijgers L et al.: Improved diagnosis of trichomonas vaginalis infection by PCR using vaginal swabs and urine specimens compared to diagnosis by wet mount microscopy, culture, and fluorescent staining. J Clin Microbiol 1999, 37, 4127–4130
  • [21] Donders GGG: Microscopy of bacterial flora on fresh vaginal smears. Infect Dis Obstet Gynecol 1995, 7, 12–13
  • [22] Spiegel CA, Amsel R, Holmes KK: Diagnosis of bacterial vaginosis by direct Gram-stain of vaginal fluid. J Clin Microbiol 1993, 18, 170–177
  • [23] Sonnex C: The amine test: a simple, rapid, inexpensive method for diagnosing bacterial vaginosis. Br J Obstet Gynecol 1995, 102, 160–161 [Crossref]
  • [24] Nugent RP, Krohn MA, Hillier SL: Reliability of diagnosing bacterial vaginosis is improved by a standard method of Gram stain interpretation. J Clin Microbiol 1991, 29, 297–301 [PubMed]
  • [25] Donders GGG: Definition and classification of abnormal vaginal flora. Best Pract Res Clin Obstet Gynaecol 2007, 21, 355–373 http://dx.doi.org/10.1016/j.bpobgyn.2007.01.002[Crossref]
  • [26] Donders GGG, Desmyter L, Vereecken A: Vaginitis. Lactobacillary grades and lactate producing bacteria in the vagina. N Engl J Med 1998, 338, 1548 http://dx.doi.org/10.1056/NEJM199805213382116[Crossref]
  • [27] Donders GGG, Vereecken A, Bosmans E et al.: Definition of a type of abnormal vaginal flora that is distinct from bacterial vaginosis: aerobic vaginitis. Br J Obstet Gynaecol 2002, 109, 1–10
  • [28] Cibley LJ: Cytolytic vaginosis. Am J Obstet Gynecol 1991, 165, 1245–1249
  • [29] Menon R, Fortunate SJ: Infection and the role of inflammation in preterm premature rupture of the membrane. Best Pract Res Clin Obstet Gynecol 2007, 21, 467–478 http://dx.doi.org/10.1016/j.bpobgyn.2007.01.008[Crossref]
  • [30] Bjerkedahl T, Czeizel AE, Hosmer DW: Birth weight of single livebirths and weight specific early neonatal mortality in Hungary and Norway. Paediat Perinat Epidemiol 1983, 3, 29–40 http://dx.doi.org/10.1111/j.1365-3016.1989.tb00367.x[Crossref]
  • [31] Divers MJ, Lilford RJ: Infection and preterm labor: a meta-analysis. Contemp Rev Obstet Gynecol 1993, 5, 71–84
  • [32] Lettieri L, Vintaileos AM, Rodis JF, et al.: Does “idiopathic” preterm labor resulting in preterm birth exist? Am J Obstet Gynecol 1993, 168, 1480–1485 [Crossref][PubMed]
  • [33] Chin BM, Lamon RF: The microbiology of preterm labor and delivery. Contemp Rev Obstet Gynaecol 1997, 9, 285–286
  • [34] McGregor JA, French JI, Richter R et al.: Antenatal microbiological maternal risk factors associated with prematurity. Am J Obstet Gynecol 1990, 163, 1465–1473
  • [35] Korn AP, Bolan G, Padian N et al.: Plasma cell endometritis in women with symptomatic bacterial vaginosis. Obstet Gynecol 1981, 85, 387–388 http://dx.doi.org/10.1016/0029-7844(94)00400-8[Crossref]
  • [36] Owen J, Groome LJ, Hauth JC: Randomised trial of prophylactic antibiotic therapy after preterm rupture. Amer J Obstet Gynecol 1993, 169, 976–981
  • [37] Mercer BM, Miodovnik M, Thurnau GR, et al.: Antibiotic therapy for reduction of infant morbidity after preterm premature rupture of the membranes. A randomized controlled trial. J Am Med Ass 1997, 278, 989–995 http://dx.doi.org/10.1001/jama.278.12.989[Crossref]
  • [38] Brucklehurst P, Hannah M, McDonald H: Interventions for treating bacterial vaginosis in pregnancy. Cochrane Database Syst Rev 2000, (2), CD000262
  • [39] Leitich H, Brunhauer M, Bodner-Adler B, et al.: Antibiotic treatment of bacterial vaginosis in pregnancy: a meta-analysis. Am J Obstet Gynecol 2003, 188, 752–758 http://dx.doi.org/10.1067/mob.2003.167[Crossref]
  • [40] Romero R, Chaiworaponga T, Kuivaniemi H, Tromp G: Bacterial vaginosis, the inflammatory response and the risk of preterm birth: a role for genetic epidemiology in the prevention of preterm birth. Am J Obstet Gynecol 2004, 190, 1509–1519 http://dx.doi.org/10.1016/j.ajog.2004.01.002[Crossref]
  • [41] Cotch MF, Hillier SL, Gibbs RS, Eschenback DA: Epidemiology and outcomes associated with moderate to heavy Candida colonisation during pregnancy. Am J Obstet Gynecol 1998, 178, 374–380 http://dx.doi.org/10.1016/S0002-9378(98)80028-8[Crossref]
  • [42] Czeizel AE, Rockenbauer M: A lower rate of preterm birth after clotrimazole therapy during pregnancy. Paediat Perinat Epid 1999, 13, 58–64 http://dx.doi.org/10.1046/j.1365-3016.1999.00157.x[Crossref]
  • [43] Czeizel AE, Fladung B, Vargha P: Preterm birth reduction after clotrimazole treatment during pregnancy. Eur J Obstet Gynecol Reprod Biol 2004, 114, 157–163 http://dx.doi.org/10.1016/j.ejogrb.2004.02.011[Crossref]
  • [44] Czeizel AE, Puhó E, Kazy Z: The use of data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities for the evaluation of birth outcomes beyond congenital abnormalities. Cent Eur J Publ Hlth 2007, 15, 147–153
  • [45] Kiss H, Petricevic L, Husslein P: Prospective randomised controlled trial of an infection screening programme to reduce the rate of preterm delivery. Br Med J 2004, 329, 371–374 http://dx.doi.org/10.1136/bmj.38169.519653.EB[Crossref]
  • [46] Okun N, Gronau KA, Hannah ME: Antibiotics for bacterial vaginosis or Trichomonas vaginalis in pregnancy: a systematic review. Obstet Gynecol 2005, 105, 857–868 http://dx.doi.org/10.1097/01.AOG.0000157108.32059.8f[Crossref]
  • [47] Genc MR, Schantz-Dunn J: The role of gene-environment interaction in predicting adverse pregnancy outcome. Best Pract Res Clin Obstet Gynaecol 2007, 21, 491–504 http://dx.doi.org/10.1016/j.bpobgyn.2007.01.009[Crossref]
  • [48] Kenyon SL, Taylor DJ, Tarnow-Mordi W: Broad spectrum antibiotics for spontaneous preterm labour: The ORACLE II. Randomized trial. ORACLE Collaborative Group. Lancet 2001, 357, 989–994 http://dx.doi.org/10.1016/S0140-6736(00)04234-3[Crossref]
  • [49] McGregor JA, French JI, Parker R, et al.: Prevention of premature birth by screening and treatment for common genital tract infections: results of a prospective controlled evaluation. Am J Obstet Gynecol 1995, 173, 157–167 http://dx.doi.org/10.1016/0002-9378(95)90184-1[Crossref]
  • [50] Lamont RF: Can antibiotics prevent preterm birth - the pro and con debate. Br J Obstet Gynaecol 2005, 112, Suppl.1, 67–73
  • [51] Teichmann AT, Steigerwald U: Infektionen in Gynekologie und Geburtshilfe. Wissenschaftliche Verlagsgeselschaft. Stuttgart. 1994
  • [52] Engelmann E. Sproßpilze. In: Hahn H, Falke D, Kaufmann SHE, Ullmann U (eds) Medizinische Mikrobiologie und Infektologie. Springer. Berlin. 1999. pp. 693–703
  • [53] Ugwumadu A: Role of antibiotic therapy for bacterial vaginosis and intermediate flora in pregnancy. Best Pract Res Clin Obstet Gynaecol 2007, 21, 391–402 http://dx.doi.org/10.1016/j.bpobgyn.2007.01.001[Crossref]

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-010-0049-y
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.