The operative deliveries can expose the fetus to acute and systemic hypoxia along with an increase in perinatal morbidity. The aim of this study was to reveal any relationship between delivery type and Chitotriosidase and Troponin T levels in cord blood. Ninety babies born in Ankara Etlik Maternity and Women’s Health Teaching Hospital were involved in the study. The babies were divided into three groups; Group 1: Normal vaginal; Group 2: Caesarean section; Group 3: Forceps application. Cord blood samples were drawn from umbilical arteries of the babies soon after the birth. Chitotriosidase enzyme activities in group 3 (141 nmol/ml/h (0–246)) were found higher than groups 1 (100 nmol/ml/h (0–208)) and 2 (91 nmol/ml/h (0–202)) (p<0.01 and p<0.03 respectively). Although cardiac Troponin T levels were higher in group 3, the difference among groups was not statistically significant (p=0.79). Acute or systemic hypoxic exposure of the organism gives rise to a microvascular response characterized by interactions between leukocytes and endothelium. We are hypothesizing that the high levels of chitotriosidase found in the forceps group were due to hypoxia, and that chitotriosidase level can be used as a marker of acute and systemic hypoxia.