Comparison of the effect of sevoflurane and desflurane on postoperative arrhythmia and QT dispersion

• Authors: Muhammet Gozdemir , Ekrem Yeter , Murat Akcay , Elvin Kurdoglu , Tülin Gumus , Telat Keleş , Emine Bilen , Orhan Kanbak
• Languages of publication: EN

Abstracts

EN

The aim of this study was to investigate the effect of sevoflurane and desflurane on cardiac arrhythmias in adult patients who will be anesthetized. A total of 40 patients who were in the ASA I–II group and who were to undergo elective surgery were included in the study. No pre-medication was administered to the patients. They were monitored with the Holter equipment at preoperative 24 hours, and also at postoperative 24 hours on condition that Holter monitoring will begin before induction. Following routine monitoring, the patients were randomly divided into two equal groups; group one was given sevoflurane and group two was given desflurane. In this study, desflurane and sevoflurane resulted in both a significant prolongation of QT and QTc and a significant increase in QT and QTc dispersion when compared with the basal values. In the sevoflurane group, there was no significant increase in postoperative ventricular arrhythmia, compared to that during the preoperative period. However, this increase was significant in the desflurane group (p = 0.009). Sevoflurane and desflurane result in an increase in QT dispersion. Postoperative rhythmic control should carefully be monitored, especially in the desflurane group.

Keywords

EN

Desflurane; Sevoflurane; QT; Holter; Arrhythmia

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2010
• Volume: 5
• Issue: 2
• Pages: 209-214

Dates

published

1 - 4 - 2010

online

17 - 4 - 2010

Contributors

author

Muhammet Gozdemir

• Department of Anesthesiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Ekrem Yeter

• Department of Cardiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Murat Akcay

• Department of Cardiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Elvin Kurdoglu

• Department of Anesthesiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Tülin Gumus

• Department of Anesthesiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Telat Keleş

• Department of Cardiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Emine Bilen

• Department of Cardiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

author

Orhan Kanbak

• Department of Anesthesiology, Atatürk Education and Research Hospital, 06800, Ankara, Turkey

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Identifiers

DOI

10.2478/s11536-009-0115-5