Risk factors for osteoporosis in healthy males

• Authors: Özlem Seven , Hale Karapolat , Sibel Eyigor , Yesim Kirazlı , Berrin Durmaz
• Languages of publication: EN

Abstracts

EN

We investigated the correlation of bone mineral density (BMD) with risk factors and laboratory parameters (e.g., markers of bone turnover, biochemical indicators, and hormonal factors) in males without secondary osteoporosis. A total of 105 males were divided into two groups: Group 1 (n: 52) <60 years, and Group 2 (n:53) ≥ 60 years. The subjects were evaluated for risk factors (European Vertebral Osteoporosis Study (EVOS) and BMD) and for biochemical (i.e., blood calcium, blood phosphorus, urinary calcium/phosphorus, creatinine clearance, osteocalcin, and deoxypyridinoline) and hormonal markers (follicle-stimulating hormone [FSH], luteinizing hormone [LH], free testosterone [fT], and parathyroid [PTH]) of bone mineral metabolism. In Group 1, no significant relationship was observed between risk factors for both lumbar and femoral neck BMDs and risk factors and laboratory parameters (p>0.05). On the other hand, we observed in Group 2 a significant positive correlation between lumbar BMD and BMI, BMI at 25 years of age, and fT; in the same group, a negative correlation between lumbar BMD and deoxypyridinoline (p<0.05) was seen. We saw a significant positive correlation between femoral neck BMD and BMI, BMI at 25 years of age, and daily activities of life in Group 2. In addition, we saw a negative correlation between femoral neck BMD and height difference, fT, LH, and deoxypyridinoline in Group 2 (p<0.05). Risk factors for male osteoporosis were multifactorial: demographic and clinical data (difference of height, BMI, physical activity) together with biochemical and hormonal data (deoxypyridinoline, fT, LH) were significant, and most of the risk factors analyzed were related to bone loss in the proximal femur.

Keywords

EN

Male; Osteoporosis; Risk factors

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2010
• Volume: 5
• Issue: 5
• Pages: 593-600

Dates

published

1 - 10 - 2010

online

20 - 8 - 2010

Contributors

author

Özlem Seven

• Medical Faculty Physical Medicine and Rehabilitation Department, Ege University, 35100, Bornova, Izmir, Turkey

author

Hale Karapolat

• Medical Faculty Physical Medicine and Rehabilitation Department, Ege University, 35100, Bornova, Izmir, Turkey

author

Sibel Eyigor

• Medical Faculty Physical Medicine and Rehabilitation Department, Ege University, 35100, Bornova, Izmir, Turkey

author

Yesim Kirazlı

• Medical Faculty Physical Medicine and Rehabilitation Department, Ege University, 35100, Bornova, Izmir, Turkey

author

Berrin Durmaz

• Medical Faculty Physical Medicine and Rehabilitation Department, Ege University, 35100, Bornova, Izmir, Turkey

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Identifiers

DOI

10.2478/s11536-009-0111-9