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2010 | 5 | 2 | 235-242
Article title

Is adequate and balanced nutrition during pregnancy more effective than iron and folic acid supplements?

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EN
Abstracts
EN
To provide instruction for pregnant women regarding adequate and balanced nutrition and determine whether iron and folic acid supplementation is essential. The research was an experimental clinical intervention. The study was conducted between March 2004 and May 2005 with 80 pregnant volunteers. The study participants were in their 16th to 24th weeks of pregnancy; all participants were healthy, carried only one fetus, and successfully completed their pregnancy. All participants were instructed about adequate and balanced nutrition. Until the participants gave birth, 40 (Group 1) consumed an iron-rich diet that was equivalent to the inclusion of a supplement containing 100 mg Ferro III plus 0,35 mg folic acid; the other group (Group 2) was also instructed in proper nutrition and was given by a gynecologist 1 tablet (100 mg) Ferro III hydroxide polymaltose complex and iron pharmaceutical with 0,35 mg folic acid (Maltofer Fol). In both groups, before and after the instruction, consumption frequency was noted, and the levels of serum ferritin, serum iron, total iron-binding capacity, folic acid, and vitamin B12 in the blood were determined at monthly intervals. Between the two groups, no statistical difference was found with regard to age, number of pregnancies, weight before pregnancy, body mass index (BMI) before pregnancy, and weight of the newborn (p>0,05). At the end of the study, the hemoglobin, hematocrit, and serum ferritin levels decreased considerably in both groups compared to the initial values (p<0.01). No statistically significant difference in serum ferritin levels could be found between the two groups (p>0,05). The comparison of Group I and Group II in terms of nutritional status (average energy and food consumption) in the pre-instruction and post-instruction periods revealed that intake of total protein, heme protein, dietary fiber, folic acid, carotene, vitamins A, B1, B2, B6, C, and B12, potassium, calcium, phosphorus, iron, and zinc was higher in Group I in the post-instruction period (p=0.000); no statistically significant change in nutritional status during pregnancy was observed in Group II. Conclusion: Medical diet programs with iron sources are examined in association with food consumption. Assessment of hematological results suggests that, during pregnancy, each patient should receive a specific dose, rather than a routine dose, of iron and folic acid.
Keywords
Publisher

Journal
Year
Volume
5
Issue
2
Pages
235-242
Physical description
Dates
published
1 - 4 - 2010
online
17 - 4 - 2010
Contributors
  • Health Services, Ondokuz Mayis University, 55139, Samsun, Turkey
author
  • Department of Obstetrics and Gynecology, Ondokuz Mayis University Hospital, 55139, Samsun, Turkey
author
  • Department of Obstetrics and Gynecology, Ondokuz Mayis University Hospital, 55139, Samsun, Turkey
author
  • Department of Rheumatology, Fatih Sultan Mehmet Training and Research Hospital, 34752, Istanbul, Turkey
References
  • [1] Beard JL. Effectiveness and strategies of iron supplementation during pregnancy. Am J Clin Nutr 2000;71(Suppl 5);1288S–94S
  • [2] Picciano MF. Pregnancy and lactation. In: Ziegler EE, Filer LJ (eds). Present knowledge in nutrition. Washington, DC: ILSI Pres, 1996: 384–95
  • [3] Barker DJP. Fetal origins of coronary heart disease. BMJ 1995; 311;171
  • [4] Susser M, Smith Z. Timing in prenatal nutrittion: a reprise of the Dutch Famine study, Nutr Rev 1994; 52;84
  • [5] World Health Organization. The prevalence of anaemia in women; a tabulation of available information. 2nd ed. Geneva: World Health Organization. 1992
  • [6] Koller O. The clinical significance of hemodilition during pregnancy. Obset Gynecol Surv 1982; 37;649 [Crossref]
  • [7] De Maeyer EM. Preventing and controlling iron deficiency anemia through primary health care. World Health Organization, Geneva; 1989
  • [8] Türkiye Nüfus ve Sağlık Araştırması 1998. Sağlık Bakanlığı Hacettepe Üniversitesi Nüfus Etütleri Enstitüsü, Macro International Ankara, 1999
  • [9] Andrews N.C. Iron Metabolısm and Absorption. Rev Clin Exp Hematol 2004; 4; 283–289 http://dx.doi.org/10.1046/j.1468-0734.2000.00021.x[Crossref]
  • [10] Subar AF, et al; Dietary sources of nutritients among us adults, 1989 to 1991, J Am Diet Assoc 1998; 98; 537 http://dx.doi.org/10.1016/S0002-8223(98)00122-9[Crossref]
  • [11] Sloan NL, Jordan E, Winikoff B. Effects of iron supplementation on metarnal hematologic status in pregnancy. Am J of Public Health 2002; 92; 288–293 http://dx.doi.org/10.2105/AJPH.92.2.288[Crossref]
  • [12] Haram K, Nilsen ST. Iron supplementation in pregnancy-evidence and controversies. Acta Obstetrica Gynecologica Scandinava 2001; 80; 683–688
  • [13] Schol TO, Reilly T. Anemia, iron and pregnacy outcome. Br J Obstet Gynaecol 2000;130; 443–447
  • [14] Allen LH. Anemia and iron deficiency: effects on pregnancy outcome. Am J of Clinical Nutrition 2000; 71; 1280–1284 [WoS]
  • [15] Graves BW, Barger MK. A conservative approach to iron supplementation during pregnancy. Journal of Midwifery&Women’s Health 2001; 46; 159–165
  • [16] Stefensen R, Varming K, Jersild C. Determination of gene frequences for two common haemochromatosis mutations in the Danish Population by a novel polymerase chain reaction with sequence specific primers. Tissue Antigens 1998; 52; 230–235 http://dx.doi.org/10.1111/j.1399-0039.1998.tb03037.x[Crossref]
  • [17] Allen CH. Nutritional Supplementation for the pregnant women. Clinical Obstetrics and Gynecology 1994; 37; 587–595 http://dx.doi.org/10.1097/00003081-199409000-00011[Crossref]
  • [18] Ozenoglu A. Gebelikte tartı alımı ve besin ögeleri gereksinmesi. Jinekoloji Obstetrik Pediatri Dergisi 1998; 6; 21–28. (Journal in Turkish)
  • [19] Elmacıoğlu F. Anne ve Bebek Beslenmesi Hatipoğlu Yayınevi, Ankara, 2008. (Book in Turkish)
  • [20] BeBiS “Beslenme Bilgi Sistemi” Nutrition data software program. I. version, 2002
  • [21] SPSS for windows, Release 12 September 2002
  • [22] Davidson L, et al: Imporoving iron absorbsion from a Peruvian school brekfast meal by adding ascorbic asit or Na2 EDTA. Am J Clin Nutr 2001; 73; 283
  • [23] Mahan KL, Stump SE. Krause’s Food, Nutrition &Diet Therapy, 11th Edition, 2004
  • [24] Institute of Medicine, Food and Nutrition Board. Iron deficiency anemia: quidelines for preventior, detection and management among U.S. Children and women of childbearıng age. Washington DC; National Academy Press, 1993
  • [25] Milman N, Byg KE, Agger OA. Hemoglobin and Erythrocyte Indıces During Normal Pregnancy and Postpartum in 206 Women With and Without Iron Supplementation. Acta Obstet Gynecol Scand 2000; 79; 89–98 http://dx.doi.org/10.1034/j.1600-0412.2000.079002089.x[Crossref]
  • [26] Kimya Y, Cengiz C. Gebeliğe Bağlı Annedeki Sistemik Değişiklikler. Beksac S, Demir N, Koş A, et all. (editors) Obstetrik Maternal -Fetal Tıp&Perinatoloji. Nobel Tıp Kitapevi; 23:676–681, Istanbul, 2001. (Book in Turkish)
  • [27] Paulakka J, Janne O, Pakarinen A, Jarninen PA, Vikho R. Serum Ferritin as a Measure of Iron Stores During After Normal Pregnancy With and Without Iron Supplements. Acta Obstet Gynecol Scand 1980; Suppl;95; 43–51 http://dx.doi.org/10.3109/00016348009156379[Crossref]
  • [28] Thompsen JK. Prien-Lavsen JC, Devantier A, Fogh Andersen N. Low Dose Iron Supplementation Does not Cover the Need for Iron During Pregnancy. Acta Obstet Gynecol Scand; 1993; 72; 93–98 http://dx.doi.org/10.3109/00016349309023419[Crossref]
  • [29] Romslo I, Haram K, Sagen N, Augesen K. Iron Requirement in Normal Pregnancy as Assessed by Serum Ferritin, Serum Transferrin Saturation and Erythrocyte Protoporphyrin Determinations. Br J Obstet Gynaecol 1983; 90; 101 [Crossref][PubMed]
  • [30] Schwartz JW, Thurnau RG. Iron Deficiency Anemia in Pregnancy. Clinical Obstetrics and Gynecology 1995; 38; 443–454 http://dx.doi.org/10.1097/00003081-199509000-00004[Crossref]
  • [31] Baysal A. Mineral ve Vitaminlerle Besinlerde Bulunan Diğer Ögelerin Çeşitli Hastalıkların Diyet Tedavilerinde Kullanımı. Beslenme ve Diyet Dergisi 2000; 29
  • [32] Casanueva E, Viteri FE. Iron and Oxidative Stres in Pregnancy. J Nutr 2003; 133; 1700–1708
  • [33] Milman N, Agger AO, Nielsen OJ. Iron Supplementation During Pregnancy: Effect on Iron Status Markers, Serum Erythropoitein and Human Placental Lactogen: A placebo Study in 207 Women, Danish Med Bull 1991; 38; 471–476
  • [34] Allen LH. Pregnancy and Iron Deficiency: Unresolved Issues. Nutr Rev 1997; 55; 91–101 http://dx.doi.org/10.1111/j.1753-4887.1997.tb06460.x[Crossref]
  • [35] Milman N, Gradual N, Agger AO. Iron Status Markers During Pregnancy. J Intern Med 1995; 232; 261–267 http://dx.doi.org/10.1111/j.1365-2796.1995.tb01174.x[Crossref]
  • [36] Steer PJ. Maternal Hemoglobin Concentration and Birth Weight. Am J Clin Nutr 2000; 71; 1285–88
  • [37] Açkurt F, Löker M, Wetherilt H. Pre-ve Post-natal Dönemlerdeki Annelerin Besin Tüketimi Kan ve Anne Sütü Vitamin ve Mineral Düzeylerinin Değerlendirilmesi, Beslenme ve Diyet Dergisi 1996; 25; 5–15. (Journal in Turkish)
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-009-0099-1
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