The effects of vitamin E and selenium on blood flow to experimental skin burns in rats using the 133Xe clearance technique

• Authors: Erhan Varoglu , Bedri Seven , Kenan Gumustekin , Omer Aktas , Ali Sahin , Senol Dane
• Languages of publication: EN

Abstracts

EN

The aim of the present experimental study was to determine and to compare the effects of vitamin E and of selenium on the blood flow to a wound region in rats, using the xenon-133 (133Xe) clearance technique. Burn wounds were made on the right thighs of rats followed by oral administration of vitamin E or selenium for a period of 10 days. The effect of vitamin E and of selenium individually on blood flow in the wound region was assessed before and after oral administration using the 133Xe clearance technique. Both vitamin E and selenium significantly increased the blood flow in the wound region (P<0.05). Our results in rats suggest that both vitamin E and selenium have beneficial effects on the skin wound healing process by increasing the skin blood flow.

Keywords

EN

Vitamin E; Selenium; Wound healing; Blood flow; Xenon-133

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2010
• Volume: 5
• Issue: 2
• Pages: 219-223

Dates

published

1 - 4 - 2010

online

17 - 4 - 2010

Contributors

author

Erhan Varoglu

• Department of Nuclear Medicine, Ataturk University, Medical School, 25240, Erzurum, Turkey

author

Bedri Seven

• Department of Nuclear Medicine, Ataturk University, Medical School, 25240, Erzurum, Turkey

author

Kenan Gumustekin

• Department of Physiology, Ataturk University, Medical School, 25240, Erzurum, Turkey

author

Omer Aktas

• Department of Physiology, Ataturk University, Medical School, 25240, Erzurum, Turkey

author

Ali Sahin

• Department of Nuclear Medicine, Ataturk University, Medical School, 25240, Erzurum, Turkey

author

Senol Dane

• Department of Physiology, Ataturk University, Medical School, 25240, Erzurum, Turkey

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Identifiers

DOI

10.2478/s11536-009-0081-y