Transfusion associated in-hospital mortality and morbidity in isolated Coronary Artery Bypass Graft surgery

• Authors: Abbas Salehiomran , Hossein Ahmadi , Abbasali Karimi , Mokhtar Tazik , Samaneh Dowlatshahi , Mahmood Fathollahi , Seyed Abbasi
• Languages of publication: EN

Abstracts

EN

Transfusion after cardiac surgery is very common. This rate varies between institutions and has remained high despite established transfusion guidelines. We analyzed our database of patients who underwent isolated CABG (Coronary Artery Bypass Graft) to determine the predictive factors of homologous transfusion and associated postoperative morbidity, mortality and resource utilization. All 14,152 patients who underwent first-time isolated CABG, with or without cardiopulmonary bypass (CPB) who had postoperative homologous transfusion between February 2002 and March 2008 in Tehran Heart Center, were evaluated retrospectively. Overall, 16.5% of patients received transfusion. Transfused patients demonstrated a significantly higher incidence of postoperative complications (cardiac, infectious, ischemic, reoperation) and mortality (p<0.001). Homologous blood transfusion effect on mortality, morbidity and resource utilization. By Multivariable logistic regression analysis adjusted for confounders: Homologous blood transfusion effect on Mortality (30-days) (OR=3.976, p<0.0001), Prolonged ventilation hours (OR=4.755, p<0.0001), Total ICU hours (β =14.599, p<0.0001), Hospital length of stay (β =1.141, p<0.0001), Post surgery length of stay (β =0.955, p<0.0001). We conclude that the isolated CABG patients receiving blood transfusion have significantly higher mortality, morbidity and resource utilization. Homologous blood transfusion is an independent factor of increased resource utilization, morbidity and mortality.

Keywords

EN

Transfusion; CABG; Mortality; Morbidity

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2009
• Volume: 4
• Issue: 3
• Pages: 286-292

Dates

published

1 - 9 - 2009

online

3 - 7 - 2009

Contributors

author

Abbas Salehiomran

• Cardiovascular Surgery Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

author

Hossein Ahmadi

• Cardiovascular Surgery Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

author

Abbasali Karimi

• Cardiovascular Surgery Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

author

Mokhtar Tazik

• Clinical Reaserch Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

author

Samaneh Dowlatshahi

• Clinical Reaserch Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

author

Mahmood Fathollahi

• Clinical Reaserch Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

author

Seyed Abbasi

• Clinical Reaserch Department, Tehran Heart Center, Medical Sciences/ Univercity of Tehran, Tehran, 1411713138, Iran

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Identifiers

DOI

10.2478/s11536-009-0044-3