Results after radical surgical treatment for advanced carcinoma of hypopharynx

• Authors: Oğuz Hasdemir , Cavit Çöl , Oktay Büyükaşık , Nihat Akçayöz
• Languages of publication: EN

Abstracts

EN

The aim of the study was to investigate patients with hypopharyngeal cancer. And this study focuses on a case series with hypopharynx cancer and cervical oesophageal cancer invading the hypopharynx. There were 13 cases over a period of 8 years, treated with pharyngo-laryngo-esophagectomy (PLE) and cervical lymph node dissection. In 10 of the patients, reconstruction was done with gastric pull-up (GP). In 3 of the 10 patients gastric reconstruction was added to aid in pyloric drainage (2 pyloromyotomy and 1 pyloroplasty) but the remaining 7 patients did not receive such procedures. The reconstruction of the digestive system after PLE is still a matter of debate. GP method is the most frequently preferred method for reconstruction. We believe that a more important problem than gastric drainage is the reflux of the gastric content and pyloric drainage which will not have a positive effect for solving this clinical situation. But we need bigger series for analyze of this specific condition.

Keywords

EN

Carcinoma of hypopharynx; Pharyngo-laryngo-esophagectomy; Gastric pull up

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2009
• Volume: 4
• Issue: 4
• Pages: 512-518

Dates

published

1 - 12 - 2009

online

3 - 10 - 2009

Contributors

author

Oğuz Hasdemir

• Department of General Surgery, Medical Faculty of Abant Izzet Baysal University, 14280, Bolu, Turkey

author

Cavit Çöl

• Department of General Surgery, Medical Faculty of Abant Izzet Baysal University, 14280, Bolu, Turkey

author

Oktay Büyükaşık

• Department of (2nd) General Surgery, Yıldırım Beyazıt Training and Research Hospital, 06110, Ankara, Turkey

author

Nihat Akçayöz

• Department of (1st) Otorhinolaryngology, Yıldırım Beyazıt Training and Research Hospital, 06110, Ankara, Turkey

References

• [1] Jones A.S., Webb C.J., Fenton J.E., Hughes J.P., Husband D.J., Winstanley J.H., A report of 50 patients with carcinoma of the hypopharnx treated by total pharynsgo-laryngo-oesophagectomy repaired by gastric transposition, Clin Otolaryngol Allied Sci., 2001, 26, 447–451 http://dx.doi.org/10.1046/j.1365-2273.2001.00480.x[Crossref]
• [2] Hao-Wei W., Pen-Yuan C., Kuang-Tai K., Chia-Hsin Y., Shyue-Yih C., Wen-Hu H., et al., A reappraisal of surgical management for squamous cell carcinoma in the pharyngoesophageal junction, J Surg Oncol., 2006, 93, 468–476 http://dx.doi.org/10.1002/jso.20472[Crossref]
• [3] Affleck D.G., Karwande S.V., Bull D.A., Haller JR., Stringham JC., Davis RK., Functional outcome and survival after pharyngolaryngoesophagectomy for cancer, Am J Surg., 2000, 180, 546–550 http://dx.doi.org/10.1016/S0002-9610(00)00517-1[Crossref]
• [4] Hancock SL., and Glatstein E., Radiation therapy of esophageal cancer, Semin Oncol., 1984, 11, 144–158
• [5] Newaishy GA., Read GA., Duncan W., Kerr GR., Results of radical radiotherapy of squamous cell carcinoma of the oesophagus, Clin Radiol., 1982, 33, 347–352 http://dx.doi.org/10.1016/S0009-9260(82)80288-2[Crossref]
• [6] Pearson JG., The value of radiotherapy in the management of oesophageal cancer, Am J Roentgenol., 1969, 105, 500–513 [Crossref]
• [7] Surkin MI., Lawson W., Biller HF., Analysis of the methods of pharyngoesophageal reconstruction, Head Neck Surg., 1984, 6, 953–970 http://dx.doi.org/10.1002/hed.2890060510[Crossref]
• [8] Stell PM., Missotten F., Singh SD., Ramadan MF., Morton RP., Mortality after surgery for hypopharyngeal cancer, Br J Surg., 1983, 70, 713–718 http://dx.doi.org/10.1002/bjs.1800701206[Crossref]
• [9] Guillamondegui OM., Meoz R., Jesse RH., Surgical treatment of squamous cell carcinoma of the pharyngeal walls, Am J Surg., 1978, 136, 474–476 http://dx.doi.org/10.1016/0002-9610(78)90264-7[Crossref]
• [10] Pesko P., Sabljak P., Bjelovic M., Stojakov D., Simic A., et al., Surgical treatment and clinical course of patients with hypopharyngeal carcinoma, Dis Esophagus., 2006, 19, 248–253 http://dx.doi.org/10.1111/j.1442-2050.2006.00585.x[Crossref]
• [11] Böttger T., Bumb P., Dutkowski P., Schlick T., Junginger T., Carcinoma of the hypopharynx and the cervical oesophagus: a surgical challenge, Eur J Surg., 1999, 165, 940–946 http://dx.doi.org/10.1080/110241599750008044[Crossref]
• [12] Peracchia A., Bardini R., Ruol A., Segalin A., Castoro C., Asolati M., et al., Surgical management of carcinoma of the hypopharynx and cervical esophagus, Hepatogastroenterology, 1990, 37, 371–375
• [13] Carlson GW., Coleman JJ., Jurkiewicz MJ., Reconstruction of the hypopharynx and cervical esophagus, Curr Probl Surg., 1993, 30, 427–472 http://dx.doi.org/10.1016/0011-3840(93)90051-H[Crossref]
• [14] AJCC: American Joint Committee on Cancer. In: AJCC cancer staging manual. New York: Springer; 2002. pp;31–46:91–98
• [15] Nakamura K., Shioyama Y., Kawashima M., Saito Y., Nakamura N., Nakata K., et al., Multi-institutional analysis of early squamous cell carcinoma of the hypopharynx treated with radical radiotherapy, Int J Rad Oncol Biol Phys, 2006, 65, 1045–1050 [Crossref]
• [16] Ferlito A., Shaha AR., Buckley JG., Rinaldo A., Selective neck dissection for hypopharyngeal cancer in the clinically negative neck: should it be bilateral?, Acta Otolaryngol., 2001, 121, 329–335 http://dx.doi.org/10.1080/000164801300102671[Crossref]
• [17] Buckley JG., MacLennan K., Cervical node metastases in laryngeal and hypopharyngeal cancer: a prospective analysis of prevalence and distribution, Head Neck., 2000, 22, 380–385 http://dx.doi.org/10.1002/1097-0347(200007)22:4<380::AID-HED11>3.0.CO;2-E[Crossref]
• [18] Triboulet JP., Mariette C., Chevalier D., Amrouni H., Surgical management of carcinoma of the hypopharynx and cervical esophagus: analysis of 209 cases. Arch Surg., 2001, 136, 1164–1170 http://dx.doi.org/10.1001/archsurg.136.10.1164[Crossref]
• [19] Inoue T., Shigematsu Y., Sato T., Treatment of carcinoma of the hypopharynx, Cancer, 1973, 31, 649–655 http://dx.doi.org/10.1002/1097-0142(197303)31:3<649::AID-CNCR2820310324>3.0.CO;2-B[Crossref]
• [20] Martins AS., Multicentricity in pharyngoesophageal tumors: argument for total pharyngolaryngoesophagectomy and gastric transposition, Head Neck., 2000, 22, 156–163 http://dx.doi.org/10.1002/(SICI)1097-0347(200003)22:2<156::AID-HED7>3.0.CO;2-Y[Crossref]
• [21] Tateda M., Shiga K., Yoshida H., Saijo S., Yokoyama J., Nishikawa H., et al., Management of the patients with hypopharyngeal cancer: Eightyear experience of Miyagi Cancer Center in Japan, Tohoku J Exp Med., 2005, 205, 65–77 http://dx.doi.org/10.1620/tjem.205.65[Crossref]
• [22] Wang HW., Chu PY., Kuo KT., Yang CH., Chang SY., Hsu WH., et al., A reappraisal of surgical management for squamous cell carcinoma in the pharyngoesophageal junction, J Surg Oncol., 2006, 93, 468–476 http://dx.doi.org/10.1002/jso.20472[Crossref]
• [23] Wight RG., Birchall MA., Stafford ND., Stanbridge RL., Management of hypopharyngeal carcinoma: a 6-year review, J R Soc Med., 1992, 85, 545–547
• [24] Spiro RH., Shah JP., Strong EW., Gerold FP., Bains MS., Gastric transposition in head and neck surgery: indications, complications and expectations, Am J Surg., 1983, 146, 483–487 http://dx.doi.org/10.1016/0002-9610(83)90236-2[Crossref]
• [25] Harrison DF., Thompson AE., Pharyngolaryngoesophagectomy with pharyngogastric anastomosis for cancer of the hypopharynx: review of 101 operations, Head Neck Surg., 1986, 8, 418–428 http://dx.doi.org/10.1002/hed.2890080605[Crossref]
• [26] Martins AS., Tincani AJ., Thyroidectomy and hypoparathyroidism in patients with pharyngoesophageal tumors, Head Neck., 2006, 28, 135–141 http://dx.doi.org/10.1002/hed.20318[Crossref]
• [27] Dudhat SB., Mistry RC., Fakih AR., Complications following gastric transposition after total laryngopharyngectomy, Eur J Surg Oncol., 1999, 25, 82–85 http://dx.doi.org/10.1053/ejso.1998.0605[Crossref]
• [28] Bussi M., Ferrero V., Riontino E., Gasparri G., Camandona M., Cortesina G., Problems in reconstructive surgery in the treatment of carcinoma of the hypopharyngoesophageal junction, J Surg Oncol., 2000, 74, 130–133 http://dx.doi.org/10.1002/1096-9098(200006)74:2<130::AID-JSO9>3.0.CO;2-9[Crossref]
• [29] Carlson GW., Schusterman MA., Guillamondegui OM., Total reconstruction of the hypopharnx and cervical esophagus: a 20-year experience, Ann Plast Surg., 1992, 29, 408–412 http://dx.doi.org/10.1097/00000637-199211000-00005[Crossref]
• [30] Morimoto S., Takahashi N., Kikuchi S., Yamahara H., Imada T., Kohno K., et al., Gastric emptying after gastric interposition for esophageal carcinoma: comparison between the anterior and posterior mediastinal approaches, Hepato-gastroenterology, 1998, 45, 2224–2227
• [31] Bemelman WA., Taat CW., Slors JF., van Lanschot JJ., Obertop H., Delayed postoperative emptying after esophageal resection is dependent on the size of the gastric substitute, J Am Coll Surg., 1995, 180, 461–464
• [32] Kraft RO., Fry WJ., DeWeese MS., Post vagotomy gastric atony, Archives of Surgery., 1964, 88, 865–871 [Crossref]
• [33] Dragstedt LR., Harper PV., Tovee EB., Woodward ER., Section of the vagus nerves to the stomach in the treatment of peptic ulcer. Complications and end results after four years, Annals of Surgery., 1947, 126, 687–699 http://dx.doi.org/10.1097/00000658-194711000-00005[Crossref]
• [34] Bevan K., Slack RW., Capper JW., Gastric atony complicating pharyngo-gastric anastomosis, J Laryngol Otol., 1987, 101, 519–521 http://dx.doi.org/10.1017/S0022215100102129[Crossref]
• [35] Mannell A., Hinder RA., San-Garde BA., The thoracic stomach: a study of gastric emptying, bile reflux and mucosal change, Br J Surg., 1984, 71, 438–441 http://dx.doi.org/10.1002/bjs.1800710611[Crossref]
• [36] Lanuti M., de Delva P.E., Wright. CD., Gaissert H.A., Wain J.C., Donahue D.M., et al., Postesophagectomy gastric outlet obstruction: role of pyloromyotomy and management with endoscopic pyloric dilatation, Eur J Cardiothorac Surg., 2007, 31, 149–153 http://dx.doi.org/10.1016/j.ejcts.2006.11.010[Crossref]
• [37] Zieren H.U., Muller J.M., Jacobi C.A., Pichlmaier H., Is pyloroplasty necessary following subtotal esophagectomy and interposition of a gastric tube with esophagogastric anastomosis in the neck?, Chirurg., 1995, 66, 319–325
• [38] Urschel J.D., Blewett C.J., Young E.M., Miller J.D., Bennett W.F., Pyloric drainage (pyloroplasty) or no drainage in gastric reconstruction after esophagectomy: A meta-analysis of randomized controlled trials, Dig Surg., 2002, 19, 160–164 http://dx.doi.org/10.1159/000064206[Crossref]

Identifiers

DOI

10.2478/s11536-009-0017-6