Inflation of diagnostic tests in hypertensive young adults: a need for diagnostic guideline?

• Authors: Alper Kirkpantur , Mustafa Arici , Bulent Altun , Cetin Turgan
• Languages of publication: EN

Abstracts

EN

The cause of hypertension in young adults (age:18–29 years) is mostly a primary condition although secondary causes are frequent in this population. Clinical files of 100 patients were reviewed to evaluate the use of diagnostic tests after completion of diagnostic work-up for hypertension. Seventy-nine patients had primary hypertension while 21 patients had secondary hypertension. Renal imaging studies, serum levels of aldosterone and plasma renin activity, and screening tests for pheochromocytoma were more likely to be performed in patients younger than 24 years, in female patients and in patients without familial history of hypertension in primary hypertensive patients (p<0.05). Renal imaging studies and screening tests for pheochromocytoma were done more frequently in patients with Stage 2 hypertension (p<0,05). Among secondary hypertensives, renal imaging studies and renal biopsy were more ordered in patients younger than 24 years, in female patients, in patients with Stage 2 hypertension and in patients without family history for hypertension (p<0.05). Mean body mass index was higher in patients with primary hypertension than patients with secondary hypertension (p<0.05). Seventy patients (70%) had undergone several screening interventions with negative results. In conclusion, a simple, stepwise diagnostic evaluation would greatly benefit the management of young hypertensives.

Keywords

EN

Hypertension; Secondary causes; Screening; Body mass index; Young adults

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2009
• Volume: 4
• Issue: 2
• Pages: 233-240

Dates

published

1 - 6 - 2009

online

27 - 3 - 2009

Contributors

author

Alper Kirkpantur

• Department of Internal Medicine, Nephrology Unit, Hacettepe University Faculty of Medicine, 06500, Ankara, Turkey

author

Mustafa Arici

• Department of Internal Medicine, Nephrology Unit, Hacettepe University Faculty of Medicine, 06500, Ankara, Turkey

author

Bulent Altun

• Department of Internal Medicine, Nephrology Unit, Hacettepe University Faculty of Medicine, 06500, Ankara, Turkey

author

Cetin Turgan

• Department of Internal Medicine, Nephrology Unit, Hacettepe University Faculty of Medicine, 06500, Ankara, Turkey

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Identifiers

DOI

10.2478/s11536-009-0003-z