Intracranial meningioma in a patient with osteogenesis imperfecta

• Authors: Parmenion Tsitsopoulos , Ioannis Anagnostopoulos , Vasileios Tsitouras , Ioannis Venizelos , Philippos Tsitsopoulos
• Languages of publication: EN

Abstracts

EN

Osteogenesis imperfecta (OI) is a heritable disorder characterized mainly by connective tissue manifestations. In dinstinct cases, several neurological features have also been described. A 46-year-old male with a known family history of OI type I presented with progressive gait disturbances and diminished muscle strength. Brain MRI scans revealed an infiltrative intracranial mass occupying both frontoparietal lobes. The patient underwent surgical intervention. The histological diagnosis was an atypical (Grade II) meningioma. The bony parts demonstrated a mixture of osseous defects due to OI and infiltration by the tumor. At one-year follow up the patient′s muscle power partially returned while repeat MRI scans were negative for tumor recurrence.

Keywords

EN

Osteogenesis Imperfecta; Meningioma; Tumor; Bone anomalies; Connective tissue

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2008
• Volume: 3
• Issue: 4
• Pages: 517-520

Dates

published

1 - 12 - 2008

online

22 - 10 - 2008

Contributors

author

Parmenion Tsitsopoulos

• Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece

author

Ioannis Anagnostopoulos

• Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece

author

Vasileios Tsitouras

• Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece

author

Ioannis Venizelos

• Department of Pathology, Hippokratio General Hospital, 54642, Thessaloniki, Greece

author

Philippos Tsitsopoulos

• Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece

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Identifiers

DOI

10.2478/s11536-008-0053-7