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Journal
2008 | 3 | 3 | 377-379
Article title

Pseudarthrosis in fibrous dysplasia treated with bone morphogenetic protein

Content
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Languages of publication
EN
Abstracts
EN
We present a case of pseudarthrosis in a patient suffering from polyostotic fibrous dysplasia of the right part of the body that was successfully treated with bone morphogenetic protein. Pseudarthrosis occurred after proximal femoral shaft fracture due to a motorcycle accident initially treated by intramedullary nailing. After revision, the patient was treated by pseudarthrosis debridement and grafting of bone morphogenetic protein-7/osteogenic protein-1, resulting in callus formation that allowed indolent full weight-bearing after 6 weeks. The underlying disease as well as the described treatment is discussed.
Publisher
Journal
Year
Volume
3
Issue
3
Pages
377-379
Physical description
Dates
published
1 - 9 - 2008
online
10 - 7 - 2008
References
  • [1] Pollandt K., Engels C., Werner M., Delling G., Fibrous dysplasia, Pathologe, 2002, 23, 351–356 http://dx.doi.org/10.1007/s00292-002-0553-1[Crossref]
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  • [3] DiCaprio M.R., Enneking W.F., Fibrous dysplasia. Pathophysiology, evaluation, and treatment, J. Bone Joint Surg. Am., 2005, 87, 1848–1864 http://dx.doi.org/10.2106/JBJS.D.02942[Crossref]
  • [4] Leet A.I., Chebli C., Kushner H., Chen C.C., Kelly M.H., Brillante B.A., et al., Fracture incidence in polyostotic fibrous dysplasia and the McCune-Albright syndrome, J. Bone Miner. Res., 2004, 19, 571–577 http://dx.doi.org/10.1359/JBMR.0301262[Crossref]
  • [5] Rodl R., Gotze C., Fibrous dysplasia, Orthopade, 2008, 37, 49–55 http://dx.doi.org/10.1007/s00132-007-1180-6[Crossref]
  • [6] Friedlaender G.E., Perry C.R., Cole J.D., Cook S.D., Cierny G., Muschler G.F., et al., Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions, J. Bone Joint Surg. Am., 2001, 83-A, Suppl 1,(Pt 2), S151–S158
  • [7] Mont M.A., Ragland P.S., Biggins B., Friedlaender G., Patel T., Cook S., et al., Use of bone morphogenetic proteins for musculoskeletal applications. An overview, J. Bone Joint Surg. Am., 2004, 86-A, Suppl 2, 41–55
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-008-0028-8
Identifiers
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