Preferences help
enabled [disable] Abstract
Number of results
2008 | 3 | 3 | 365-369
Article title

Recurrence of retroperitoneal fibrosis with pancreatic involvement - the importance of imaging methods

Title variants
Languages of publication
Retroperitoneal fibrosis (RPF) is a rare disease associated with the development of chronic inflammation and fibrogenesis in the retroperitoneal space. The disease usually manifests with acute or acute over chronic renal failure and/or urosepsis. Pancreatic involvement in RPF is rare but has been described in the literature. The diagnosis of RPF is made mainly by imaging methods. Abdominal echography scan reveals the presence of an obstruction with or without inflammation; computed tomography and magnetic resonance imaging show the type and the spreading of fibrosis. Here, we report a 50-year-old female patient diagnosed with RPF during operative intervention in 2003. Initial treatment with corticosteroids and tamoxifen lead to remission. In 2007, late recurrence was observed, with tumor-like lesions over the upper, posterior, and anterior surfaces of the pancreas, spreading to intraperitoneal structures and more pronounced on the left side. Abdominal echography on day 30 showed that corticosteroid treatment lead to a decrease in the tumor-like lesions.
Physical description
1 - 9 - 2008
10 - 7 - 2008
  • Clinic of Nephrology, University Hospital Alexandrovska, Sofia, Bulgaria
  • Department of Radiology, University Hospital Alexandrovska, Sofia, Bulgaria
  • Clinic of Nephrology, University Hospital Alexandrovska, Sofia, Bulgaria
  • Emergency Hospital Pirogov, Sofia, Bulgaria
  • Emergency Hospital Pirogov, Sofia, Bulgaria
  • Department of Urology, University Hospital Alexandrovska, Sofia, Bulgaria
  • Department of Cardiology, University Hospital St. Anna, Sofia, Bulgaria
  • [1] Vivas I., Nicolás A.I., Velázquez P., Elduayen B., Fernández-Villa T., Martínez-Cuesta A., Retroperitoneal fibrosis: typical and atypical manifestations., Br. J. Radiol., 2000, 73, 214–222
  • [2] Bonnet C., Arnaud M., Bertin P., Treves R., Gotteron RD., Idiopathic retroperitoneal fibrosis with systemic manifestations., J. Rheumatol., 1994, 21, 360–362
  • [3] Dehner L.P., Coffin C.M., Lauren V., Idiopathic fibrosclerotic disorders and other inflammatory pseudotumors., Semin. Diagn. Pathol., 1998, 15, 161–173
  • [4] Klisnick A., Fourcade J., Ruivard M., Baud O., Souweine B., Boyer L., et al., Combined idiopathic retroperitoneal and mediastinal fibrosis with pericardial involvement., Clin. Nephrol., 1999, 52, 51–55 [PubMed]
  • [5] Kuramochi S., Kawai T., Yakumaru K., Mikata A., Torikata C., Kasuga Y., et al., Multiple pulmonary hyalinizing granulomas associated with systemic idiopathic fibrosis., Acta. Pathol. Jpn., 1991, 41, 375–382
  • [6] Oguz K.K., Kiratli H., Oguz O., Cila A., Oto A., Gokoz A., Multifocal fibrosclerosis: a new case report and review of the literature., Eur. Radiol., 2002, 12, 1134–1138[Crossref]
  • [7] Duvic C., Desrame J., Leveque C., Nedelec G., Retroperitoneal fibrosis, sclerosing pancreatitis and bronchiolitis obliterans with organizing pneumonia., Nephrol. Dial. Transplant., 2004, 19, 2397–2399[Crossref]
  • [8] Cutaputti A., Burrell M.I., Boyer J.L., Pseudotumor of the pancreas associated with retroperitoneal fibrosis: a dramatic response to corticosteroid treatment., Am. J. Gastroenterol., 1995, 90, 1155–1158
  • [9] Voss S.D., Kruskal J.B., Kane R.A., Chronic inflammatory pseudotumor arising in the hepatobiliary-pancreatic system: progressive multisystemic organ involvement in four patients., M. J. Roentgenol., 1999, 173, 1049–1054 [PubMed]
  • [10] Miyajima N., Koike H., Kawaguchi M., Zen Y., Takahashi K., Hara N., Idiopathic retroperitoneal fibrosis associated with IgG4-positive-plasmacyte infiltrations and idiopathic chronic pancreatitis., Int. J. Urol., 2006, 13, 1442–1444[Crossref]
  • [11] Wu J., Catalano E., Coppola D., Retroperitoneal fibrosis (Ormond’s disease): clinical pathologic study of eight cases., Cancer. Control., 2002, 9, 432–437 [PubMed]
  • [12] Demko T.M., Diamond J.R., Groff J., Obstructive nephropathy as a result of retroperitoneal fibrosis: a review of its pathogenesis and associations., J. Am. Soc. Nephrol., 1997, 8, 684–688
  • [13] Bowie J.D., Bernstein J.R., Retroperitoneal fibrosis: ultrasound findings and case report., Clin. Ultrasound., 1976, 4, 435–437[Crossref]
Document Type
Publication order reference
YADDA identifier
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.