IL-2, IL-6 and IL-8 levels remain unaltered in the course of immunosuppressive therapy after renal transplantation

• Authors: Jacek Rysz , Eugeniusz Kocur , Robert Blaszczak , Piotr Bartnicki , Robert Stolarek , Mariusz Piechota
• Languages of publication: EN

Abstracts

EN

Cytokines regulate the immune reactions elicited by renal transplantation (RT). This study was designed to investigate the blood serum levels of IL-2, IL-6, IL-8 in 25 RT patients (10 female and 15 male, mean 5.4±2.7 yrs after RT) three times over a six-month period during standard immunosuppressive therapy with cyclosporine A, azathioprine and prednisolone. The levels of IL-2, IL-6 and IL-8 were tested with ELISA Quantikine Human Interleukin Immunoassay (R&D Systems, detection level 7,0.7 and 10 pg/cm3, respectively). There was no significant alternation of blood serum levels of IL-2, IL-6 and IL-8 in the study patients.

Keywords

EN

Cytokines; Lymphocytes; Transplantation; Immune system

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2008
• Volume: 3
• Issue: 2
• Pages: 199-202

Dates

published

1 - 6 - 2008

online

9 - 4 - 2008

Contributors

author

Jacek Rysz

• 2nd Department of Family Medicine, Medical University of Lodz, 90-549, Lodz, Poland

author

Eugeniusz Kocur

• 2nd Department of Family Medicine, Medical University of Lodz, 90-549, Lodz, Poland

author

Robert Blaszczak

• 2nd Department of Family Medicine, Medical University of Lodz, 90-549, Lodz, Poland

author

Piotr Bartnicki

• 2nd Department of Family Medicine, Medical University of Lodz, 90-549, Lodz, Poland

author

Robert Stolarek

• Department of Experimental and Clinical Physiology, Medical University of Lodz, 92-215, Lodz, Poland

author

Mariusz Piechota

• Department of Anaesthesiology and Intensive Care Unit, University Hospital No. 5 in Lodz, Medical University of Lodz, 90-647, Lodz, Poland

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Identifiers

DOI

10.2478/s11536-008-0011-4