PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2008 | 3 | 3 | 308-314
Article title

Association between periodontal disease and coronary artery disease

Content
Title variants
Languages of publication
EN
Abstracts
EN
The etiology of coronary artery disease (CAD) is multifunctional. There is increasing evidence that dental infections could play a role in the initiation and development of CAD. In a case control double blind study, one hundred male and female (mean age 51 ± 9.4) angiographically documented CAD, compared with one hundred male and female patients (mean age 50.6 ± 9) with angiographically negative coronary artery. All the patients (cases and control) underwent dental examination for the presence and severity of periodontitis by a dentist who was oblivious the result of the angiography performed. The association between periodontal disease status and CAD was significant (P=0.011); periodontitis was apparently more frequent in CAD positive patients than in control (86% versus 61%). Adjustment of coronary risk factors (smoking, DM, hypertension and hyperlipidemia) in both cases and control groups suggests that the association between periodontitis and CAD in our study was independent of coronary risk factors. There is increasing evidence that dental infection, especially aerobic organisms which have capability of aggregation of platelets, is the most important cause. Dental infection would be an independent risk factor for CAD.
Publisher

Journal
Year
Volume
3
Issue
3
Pages
308-314
Physical description
Dates
published
1 - 9 - 2008
online
10 - 7 - 2008
Contributors
  • Cardiovascular Research Center, Shiraz University of Medical Sciences, Shiraz, Iran, Zibaeem2@sums.ac.ir
References
  • [1] Rapp A.H., Lange R.A., Early management of acute myocardial infarction. Fam. Prac. Recen., 1992, 21, 69–80
  • [2] Mattila K.J., Valtonen V.V., Nieminen M.S., Asikainen S, Role of infection as risk factor for atherosclerosis, myocardial infarction, and strike, Clin. Infect. Dis., 1998, 26, 719–734 http://dx.doi.org/10.1086/514570[Crossref]
  • [3] Solver J., Martin A., McBride B., Experimental transient bacteremias in human subjects with varying degree of plaque accumulation and gingival inflammation, J. Clin. Periodontal., 1980, 4, 92–99 http://dx.doi.org/10.1111/j.1600-051X.1977.tb01888.x[Crossref]
  • [4] Haraszthy V., Zambon J., Travisan M., Zeid M., Genco R., Identification of periodontal pathogens in atheromatous plaques, J. Periodontal. 2000, 71, 1554–1561 http://dx.doi.org/10.1902/jop.2000.71.10.1554[Crossref]
  • [5] Herzberg M., Mayer M., Effect of oral flora on platelets: Possible consequence in cardiovascular disease, J. Periodontol., 1996, 67, 1138–1142
  • [6] Beck J., Garcia R., Heiss G., Vokans P.S., Offenbacher S., Periodontal disease and cardiovascular disease, J. Periodontal., 1996, 67, 1123–1137
  • [7] Jishipura K.J., Rimm E.B., Douglass C.W., Triechopoulos D., Ascherio A., Willet W.C., Poor oral health and coronary artery disease, J. Dent. Res. 1996, 75, 1631–1636
  • [8] De Stefano F., Anda R.F., Kahn H.S., Willkiamson D.F., Russell C.M., Dental disease and risk of coronary heart disease and mortality, Br. Med. J., 1993, 306, 688–691 http://dx.doi.org/10.1136/bmj.306.6879.688[Crossref]
  • [9] Hujoel P., Drangsholt M., Spiekerman C., De Rouen T., Periodontal disease and coronary heart disease risk, JAMA 2000, 284, 1406–1410 http://dx.doi.org/10.1001/jama.284.11.1406[Crossref]
  • [10] Howell T.H., Ridker P.M., Ajani U.A., Hennekens C.H., Christen W.G., Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians. J. Am. Coll. Cardiol., 2001, 37, 445–450 http://dx.doi.org/10.1016/S0735-1097(00)01130-X[Crossref]
  • [11] Paunio K., Impivaara O., Tiesko J., Maki J., Missing teeth and ischemic heart disease in men aged 45–64 years, Eur. Heart J., 1993, 14, 54–56
  • [12] Hujoel P.P., Dransholt M,. Spiekerman C., De Rouen T.A., Preexisting cardiovascular disease and periodontitis: A follow up study,. J. Dent. Res., 2002, 81, 186–191 [Crossref]
  • [13] Mattila K., Valtonen V., Nieminen M., Huttenen J., Dental infections and the risk of new coronary events. Prospective study of patients with documented coronary artery disease, Clin. Infect. Dis., 1995, 20, 588–592 [PubMed][Crossref]
  • [14] Mattila K., Asikanen S., Wolf J., Jousimies-Somer H., Valtonen V., Nieminen M., Age, dental infections, and coronary heart disease, Dent. Res., 2000, 79, 756–760 [Crossref]
  • [15] Emingil G., Buduneli E., Aliyev A., Akilli A., Attilla G., Association between periodontal disease and acute myocardial infarction, J. Periodontal, 2000, 71, 1882–1886 http://dx.doi.org/10.1902/jop.2000.71.12.1882[Crossref]
  • [16] Loesch W., Periodontal disease as a risk factor for heart disease, Compendium Continuing Educ. Dent., 1994, 15, 976–991
  • [17] Budoff M., Determination of coronary calcium with electron beam computed tomography, Medical Progress, 1999, 37–41
  • [18] Bini A., Mann K.G., Kudryk B.J., Schoen F.G., Noncollagenous Bone Matrix Proteins, Calcification, and Thrombosis in carotid artery atherosclerosis, Atheroscler. Thromb. Vasc. Biol., 1999, 19, 1852–1861 [Crossref]
  • [19] Morrison H., Ellison L., Taylor G., Periodontal disease and risk of fatal coronary heart and cerebrovascular diseases, J. Cardiovasc. Risk, 1999, 6, 7–11
  • [20] Baim D.S., Grossman W., Coronary angiography, In: Cardiac catheterization, Angiography, and Intervention. Baltimore, Williams and Wilkins, 1996, 204–205
  • [21] Yullanti K., Maryantoro O., Sabrinah P., The correlation between periodontal and coronary artery disease in type 2 diabetes mellitus, In: Progress of Periodontal Research and Practice in Asian Pacific Countries, Edited by: Bartold P.M., Ishikawa I., Sirirat M. Asian Pacific Society of Periodontology, 2000
  • [22] Lowe G.D.O., Kweider M., Murray G.D., Kinas D., McGowan D.A., Fibrinogen and dental disease - a coronary risk factor, In: Ernst E., Koenig W., Lowe G.D.O., Meade T., Editors. Fibrinogen - a “new” cardiovascular risk factor. Oxford: Blackwell, 1992, 187–91
  • [23] De Nardin E. The role of inflammatory and immunological mediators in periodontitis and cardiovascular disease. Ann. Periodontal., 2001, 6, 30–40 http://dx.doi.org/10.1902/annals.2001.6.1.30[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-008-0007-0
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.