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Journal
2008 | 3 | 3 | 254-256
Article title

Strategies to invent cardiovascular drugs targeting cardiac gap junctions

Authors
Content
Title variants
Languages of publication
EN
Abstracts
EN
In order to prevent and treat cardiac diseases, the author proposed strategies to invent cardiovascular drugs targeting cardiac gap junctions through summarizing the functions, physiology and pathophysiology of cardiac gap junctions. The 5 principle strategies to invent cardiovascular drugs that are suggested have great potentialities to be used as novel proposals to treat and prevent cardiac diseases.
Publisher

Journal
Year
Volume
3
Issue
3
Pages
254-256
Physical description
Dates
published
1 - 9 - 2008
online
10 - 7 - 2008
Contributors
author
  • Department of Emergency Medicine, Clinical Institute, Xin Ye County People’s Hospital, Henan Province, China, fairpersuiter@hotmail.com
References
  • [1] Wit A.L., Duffy H.S., Drug Development for Treatment of Cardiac Arrhythmias. Targeting the Gap Junctions. Am. J. Physiol. Heart Circ. Physiol., 2007, (in press) [WoS]
  • [2] Kanno S., Saffitz JE., The role of myocardial gap junctions in electrical conduction and arrhythmogenesis. Cardiovasc. Pathol., 2001, 10, 169–177. http://dx.doi.org/10.1016/S1054-8807(01)00078-3[Crossref]
  • [3] Teunissen B.E., Bierhuizen M.F., Transcriptional control of myocardial connexins. Cardiovasc. Res., 2004, 62, 246–255 http://dx.doi.org/10.1016/j.cardiores.2003.12.011[Crossref]
  • [4] Dhein S., Polontchouk L., Salameh A., Haefliger J.A., Pharmacological modulation and differential regulation of the cardiac gap junction proteins connexin 43 and connexin 40. Biol. Cell., 2002, 94, 409–422 http://dx.doi.org/10.1016/S0248-4900(02)00018-7[Crossref]
  • [5] Garcia-Dorado D., Ruiz-Meana M., Padilla F., Rodriguez-Sinovas A., Mirabet M., Gap junctionmediated intercellular communication in ischemic preconditioning. Cardiovasc. Res., 2002, 55, 456–465 http://dx.doi.org/10.1016/S0008-6363(02)00441-8[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-007-0064-9
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