Skeletal SPECT/CT of the peripheral extremities -interdisciplinary approach in orthopaedic disorders-first clinical results

• Authors: Wolfgang Wuest , Torsten Kuwert , Markus Grunewald , Werner Bautz , Raimund Forst , Andreas Mauerer , Rainer Linke
• Languages of publication: EN

Abstracts

EN

Bone scintigraphy, although quite sensitive to detect skeletal lesions, has a comparatively low specificity. Hybrid-cameras combining single-photon emission computed tomography (SPECT) and spiral-CT offer the opportunity to correlate scintigraphic information with high-quality visualization of morphology in one session. This may lead to an improvement in diagnostic accuracy and anatomic lesion localization. We present 11 patients, who underwent SPECT/CT of the feet (n=10) and hands (n = 1). The examinations were performed due to pain in foot or hand with the following suspected clinical diagnoses: arthrosis (n=1); fracture (n=3); osteomyelitis (n=4); reflex dystrophia (n=1); and, pain of unclear origin (n=2). All patients underwent SPECT/CT hybrid imaging using a dual-headed SPECT camera integrated with a 2-slice spiral CT scanner in one gantry. SPECT, CT, and SPECT/CT were evaluated independently from each other with respect to main diagnosis, anatomic lesion localization, and detection of a possible additional diagnosis. SPECT/CT improved lesion localization in 8 of 11 patients (73%) in comparison to SPECT alone, and in 4 of 11 patients (36%) in comparison to CT alone. Diagnostic accuracy was improved in 4 of 11 patients (36%) in comparison to either SPECT or CT alone. In conclusion, skeletal SPECT/CT improves diagnostic accuracy and lesion localization of orthopedic disorders in the feet and hands. The obtained results encouraged extensive studies to further investigate the potential gain in diagnostic accuracy brought about by SPECT/spiral-CT hybrid imaging in orthopedic disorders of the peripheral extremities.

Keywords

EN

Hybrid imaging; SPECT/CT; bone scintigraphy; image fusion

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2007
• Volume: 2
• Issue: 4
• Pages: 499-510

Dates

published

1 - 12 - 2007

online

1 - 12 - 2007

Contributors

author

Wolfgang Wuest

• Clinic of Nuclear Medicine, University of Erlangen-Nuernberg, D-91054, Erlangen, Germany

author

Torsten Kuwert

• Clinic of Nuclear Medicine, University of Erlangen-Nuernberg, D-91054, Erlangen, Germany

author

Markus Grunewald

author

Werner Bautz

• Institute of Radiology, University of Erlangen-Nuernberg, D-91054, Erlangen, Germany

author

Raimund Forst

• Orthopedics and Orthopedic Surgery, University of Erlangen-Nuernberg, D-91054, Erlangen, Germany

author

Andreas Mauerer

• Orthopedics and Orthopedic Surgery, University of Erlangen-Nuernberg, D-91054, Erlangen, Germany

author

Rainer Linke

• Clinic of Nuclear Medicine, University of Erlangen-Nuernberg, D-91054, Erlangen, Germany

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Identifiers

DOI

10.2478/s11536-007-0049-8