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Number of results

Journal

2006 | 1 | 3 | 306-312

Article title

Fatal outcome of pyoderma gangrenosum with multiple organ involvement and partially responding to Infliximab

Content

Title variants

Languages of publication

EN

Abstracts

EN
Pyoderma gangrenosum is an inflammatory dermatosis of uncertain etiology, often associated with chronic inflammatory bowel or rheumatoid disease. It predominantly affects the skin. A systemic organ involvement caused by aseptic neutrophilic abscesses, however, fundamentally influences the prognosis.A patient with idiopathic pyoderma gangrenosum insufficiently responded to a conventional immune suppressive therapy and the disease proceeded aggressively. During treatment with Infliximab, partial remission was achieved intermediately. However, a recurring endocarditis, led to a lethal outcome of this patient.

Publisher

Journal

Year

Volume

1

Issue

3

Pages

306-312

Physical description

Dates

published
1 - 9 - 2006
online
23 - 8 - 2006

Contributors

author
  • Department of Internal Medicine III, Friedrich Schiller University Jena, D 07740, Jena, Germany
author
  • Department of Internal Medicine III, Friedrich Schiller University Jena, D 07740, Jena, Germany
  • Department of Pathology, Friedrich Schiller University Jena, D 07740, Jena, Germany
author
  • Department of Dermatology, Friedrich Schiller University Jena, D 07743, Jena, Germany
author
  • Department of Internal Medicine III, Friedrich Schiller University Jena, D 07740, Jena, Germany
author
  • Department of Internal Medicine III, Friedrich Schiller University Jena, D 07740, Jena, Germany

References

  • [1] P. von den Driesch: “Pyoderma gangrenosum: a report of 44 cases with follow-up”, Br. J. Dermatol., Vol. 137, (1997), pp. 1000–1005. http://dx.doi.org/10.1046/j.1365-2133.1997.20022083.x[Crossref]
  • [2] I. Riahi, M. Mokni, S. Haouet et al.: “Pyoderma gangrenosum. 15 cases”, Ann. Med. Interne., Vol. 152, (2001), pp. 3–9.
  • [3] M. Vadillo, A. Jucgla, D. Podzamczer et al.: “Pyoderma gangrenosum with liver, spleen and bone involvement in a patient with chronic myelomonocytic leukaemia”, Br. J. Dermatol., Vol. 141, (1999), pp. 541–543. http://dx.doi.org/10.1046/j.1365-2133.1999.03055.x[Crossref]
  • [4] E. Miserocchi, G. Modorati, C.S. Foster et al.: “Ocular and extracutaneous involvement in pyoderma gangrenosum”, Ophthalmology, Vol. 109, (2002), pp. 1941–1943. http://dx.doi.org/10.1016/S0161-6420(02)01165-X[Crossref]
  • [5] V.G. Hubbard, A.C. Friedmann and P. Goldsmith: “Systemic pyoderma gangrenosum responding to infliximab and adalimumab”, Br. J. Dermatol., Vol. 152, (2005), pp. 1059–1061. http://dx.doi.org/10.1111/j.1365-2133.2005.06467.x[Crossref]
  • [6] G. Koester, A. Tarnower, D. Levisohn et al.: “Bullous pyoderma gangrenosum”, J. Am. Acad. Dermatol., Vol. 29, (1993), pp. 875–878. http://dx.doi.org/10.1016/0190-9622(93)70261-Q[Crossref]
  • [7] A. Hernandez-Martin, D. Arias-Palomo, G. Hermida et al.: “Oral pyoderma gangrenosum” Br. J. Dermatol., Vol. 149, (2003), pp. 663–664. http://dx.doi.org/10.1046/j.1365-2133.2003.05503.x[Crossref]
  • [8] K.S. Kennedy, M.L. Prendergast and C.D. Sooy: “Pyoderma gangrenosum of the oral cavity, nose, and larynx”, Otolaryngol. Head Neck Surg., Vol. 97, (1987), pp. 487–490.
  • [9] M.H. Tan, M. Gordon, O. Lebwohl et al.: “Improvement of Pyoderma gangrenosum and psoriasis associated with Crohn disease with anti-tumor necrosis factor alpha monoclonal antibody”, Arch. Dermatol., Vol. 137, (2001), pp. 930–933.
  • [10] M. Regueiro, J. Valentine, S. Plevy et al.: “Infliximab for treatment of pyoderma gangrenosum associated with inflammatory bowel disease”, Am. J. Gastroenterol., Vol. 98, (2003), pp. 1821–1826. http://dx.doi.org/10.1111/j.1572-0241.2003.07581.x[Crossref]

Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11536-006-0024-9
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