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Journal
2006 | 1 | 2 | 148-157
Article title

Abnormal ECG patterns during the acute phase of subarachnoid hemorrhage in patients without previous heart disease

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EN
Abstracts
EN
Subarachnoid hemorrhage (SAH) occurs primarily during early to mid-adulthood; approximately 30% of individuals with SAH die within 2 weeks, and mortality is 30% to 45%. SAH happens suddenly, without patients being aware of previous heart abnormalities. Here, we performed a pilot single cohort (historical) study to examine the hypothesis that early abnormal electrocardiographic (ECG) changes may reveal unknown but “silent” heart pathologies in SAH patients without previous heart disease (PHD). Data were collected retrospectively on 56 consecutive patients during the acute phase of SAH (29 men, 27 women; mean age 49.0 ± 6.2 years) with different degrees of neurologic deficit (Hunt-Hess scale assessment) in a 2-year period single-cohort study. Repolarization abnormalities were most frequent (p<0.05) and were independent of a history of PHD, although it corresponded to a higher risk for such abnormalities (odds ratio OR=3.21; CI95%=1.01–10.22). ECG changes in patients without PHD were similar to those in PHD patients, confirming the hypothesis that SAH is associated with previously “silent” heart pathology. The increased frequency of ECG changes in PHD patients and their high incidence in no-PHD patients suggested a neurogenic form of myocardial dysfunction following SAH. Notably, repolarization changes were more frequent in patients with less severe deficit (p<0.05), whereas rhythm and conductive abnormalities were more frequent in patients with more severe neurologic deficit.
Publisher

Journal
Year
Volume
1
Issue
2
Pages
148-157
Physical description
Dates
published
1 - 6 - 2006
online
1 - 6 - 2006
Contributors
  • Department of Cardiology, Medical University, 4000, Plovdiv, Bulgaria
  • Stroke Unit, Department of Neurology, Medical University, 4000, Plovdiv, Bulgaria
  • Stroke Unit, Department of Neurology, Medical University, 4000, Plovdiv, Bulgaria
  • Stroke Unit, Department of Neurology, Medical University, 4000, Plovdiv, Bulgaria
  • Information Services Section, Medical University Hospital ‘St. George’, 4000, Plovdiv, Bulgaria
References
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  • [13] E. Kawahara, S. Ikeda, Y. Miyahara and S. Kohno: “Role of autonomic nervous disfunction in electrocardiographic abnormalities and cardiac injury in patients with acute subarachnoid hemorrhage”, Circ. J., 67(9), (2003), pp. 753–756. http://dx.doi.org/10.1253/circj.67.753[Crossref]
  • [14] C.S. Macmillan, I.S. Grant and P.J. Andrews: “Pulmonary and cardiac sequelae of subarachnoid hemorrhage: time for active management?”, Intensive Care Med., 28(8), (2002), pp. 1012–1023. http://dx.doi.org/10.1007/s00134-002-1382-7[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-006-0018-7
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