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2006 | 1 | 1 | 12-22
Article title

Evaluation of TV cell line viral susceptibility using conventional cell culture techniques

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EN
Abstracts
EN
Despite the fact that a lot of methods have been developed for rapid virus detection, classic cell culture is still “the golden standard”. The range of viruses that can be isolated and cultured in cell line systems is often limited by the susceptibility of cells to support viral replication. Since the primary cell culture, the best cellular system available to support replication of a large number of viruses, is very expensive and diffcult to obtain, cell lines, which are easier to manipulate, are commonly used for virus growth and isolation.In two previous papers we described the TV cell line initiated by our team from a laryngeal tumor, which harbors human papillomavirus (HPV) gene sequences. In this paper we analyze its capacity to support virus replication. Depending on the virus, different cytopathic effects were produced. Comparison of viral effect observed on this cell line with the effect obtained on other cell lines has been performed. This cell line might be used in the clinical virology laboratory for virus isolation.
Publisher

Journal
Year
Volume
1
Issue
1
Pages
12-22
Physical description
Dates
published
1 - 3 - 2006
online
1 - 3 - 2006
Contributors
  • “Stefan S. Nicolau” Institute of Virology, Bucharest, Romania
  • “Stefan S. Nicolau” Institute of Virology, Bucharest, Romania
author
  • “Stefan S. Nicolau” Institute of Virology, Bucharest, Romania
author
  • “Stefan S. Nicolau” Institute of Virology, Bucharest, Romania
author
  • “Stefan S. Nicolau” Institute of Virology, Bucharest, Romania
  • “Stefan S. Nicolau” Institute of Virology, Bucharest, Romania
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11536-006-0007-x
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