Monte Carlo analysis of polymer translocation with deterministic and noisy electric fields

• Authors: Davide Valenti , Giovanni Denaro , Dominique Adorno , Nicola Pizzolato , Salvatore Zammito , Bernardo Spagnolo
• Languages of publication: EN

Abstracts

EN

Polymer translocation through the nanochannel is studied by means of a Monte Carlo approach, in the presence of a static or oscillating external electric voltage. The polymer is described as a chain molecule according to the two-dimensional “bond fluctuation model”. It moves through a piecewise linear channel, which mimics a nanopore in a biological membrane. The monomers of the chain interact with the walls of the channel, modelled as a reflecting barrier. We analyze the polymer dynamics, concentrating on the translocation time through the channel, when an external electric field is applied. By introducing a source of coloured noise, we analyze the effect of correlated random fluctuations on the polymer translocation dynamics.

Keywords

EN

polymer molecules; transport dynamics of biomolecules; noise in biological systems; Monte Carlo simulations

• Publisher: De Gruyter Open
• Journal: Open Physics
• Year: 2012
• Volume: 10
• Issue: 3
• Pages: 560-567

Dates

published

1 - 6 - 2012

online

17 - 6 - 2012

Contributors

author

Davide Valenti

• Group of Interdisciplinary Physics and CNISM, Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, I-90128, Palermo, Italy

author

Giovanni Denaro

• Group of Interdisciplinary Physics and CNISM, Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, I-90128, Palermo, Italy

author

Dominique Adorno

• Group of Interdisciplinary Physics and CNISM, Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, I-90128, Palermo, Italy

author

Nicola Pizzolato

• Group of Interdisciplinary Physics and CNISM, Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, I-90128, Palermo, Italy

author

Salvatore Zammito

• Group of Interdisciplinary Physics and CNISM, Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, I-90128, Palermo, Italy

author

Bernardo Spagnolo

• Group of Interdisciplinary Physics and CNISM, Dipartimento di Fisica, Università di Palermo, Viale delle Scienze, Edificio 18, I-90128, Palermo, Italy

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Identifiers

DOI

10.2478/s11534-012-0016-0