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Number of results

Journal

2014 | 12 | 10 | 977-993

Article title

DNA molecules site-specific immobilization and their applications

Content

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EN

Abstracts

EN
In addition to its role as a carrier of genetic information, DNA has been recognized as a construction material for the assembly of different objects and structural arrangements with nanoscale features. As a result of DNA’s self-recognition properties (based on the specific base-pairing of G-C and T-A), monolayer films of nucleic acids on solid supports have attracted an escalating attentions. Recently, numerous novel materials based on two-dimensional (2D) and three-dimensional (3D) DNA structures have been reported, which extends their utility to a large number of appliations. This review paper intends to be a new and comprehensive overview of recent strategies to site-specifically immobilized DNA on various materials, including carbonaceous substances, gold, and silica substrate, emphasizing the applications of site-specific DNA nanostructure-based devices for diagnostic, bioanalytical, food safety and environmental monitoring. Additionally, an up-to-date perspective is proposed at the end of this review.

Publisher

Journal

Year

Volume

12

Issue

10

Pages

977-993

Physical description

Dates

published
1 - 10 - 2014
online
15 - 5 - 2014

Contributors

  • University of North Carolina at Chapel Hill
author
  • Zhejiang Province Key Lab of Mariculture & Enhancement

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Document Type

Publication order reference

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YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-014-0557-8
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