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Number of results

Journal

2014 | 12 | 9 | 962-967

Article title

Controlled release of amoxicillin from bacterial cellulose membranes

Content

Title variants

Languages of publication

EN

Abstracts

EN
Bacterial cellulose (BC), a natural polymer with unique physical and mechanical properties, has several applications in the biomedical field, including drug loading and controlled drug delivery. For this study, a Box-Behnken experimental design was employed as a statistical tool to optimize the release of a model drug, amoxicillin, from BC membranes. Independent variables studied were the concentration of the drug (X1), the concentration of glycerol (X2) and the concentration of a permeation enhancer (X3). From the variables studied, drug concentration had the highest effect on drug release. Among the other independent variables, th linear and quadratic X2 terms, the linear X3 term and the interaction term X2X3 were found to affect the release of amoxicillin from bacterial cellulose membranes.

Publisher

Journal

Year

Volume

12

Issue

9

Pages

962-967

Physical description

Dates

published
1 - 9 - 2014
online
1 - 5 - 2014

Contributors

  • University “Politehnica” of Bucharest
  • University “Politehnica” of Bucharest
  • University “Politehnica” of Bucharest
author
  • University “Politehnica” of Bucharest

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-014-0541-3
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