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Journal

2013 | 11 | 10 | 1699-1709

Article title

Antioxidant and chemical properties of Inula helenium root extracts

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EN

Abstracts

EN
The objective of the paper was to investigate the chemical composition of Inula helenium roots extracts and to evaluate the antioxidant potential conferred by the chemical constituents. GC/MS and HPLC/MS techniques were used to characterize two extracts separated from Inula helenium roots by extraction with chloroform and ethyl acetate, respectively. Volatile compounds have been identified by GC from their mass spectra and retention time values, while HPLC identification of phenolic compounds was realized by comparing their retention times, UV and MS spectra with those of standards or literature data. Measurements of antioxidant activity of Inula helenium root extracts showed a variation between them, which can be correlated with the flavonoid and total phenolic contents. Both Inula helenium root extracts contain phenolic acids (caffeic, chlorogenic, dicaffeoyl quinic, hydroxibenzoic), terpenes (alantolactone) and different flavonoids (epicatechin, catechin gallate, ferulic acid-4-O-glucoside, dihydroquercetin pentosyl rutinoside, kaempherol-7-O-dipentoside, quercetin-3-O-β-glucopyranoside). In addition, the study provides preliminary data on the anti-inflammatory activity of Inula helenium root extracts, this being evaluated using the fresh egg albumin as phlogistic agent, and aspirin as reference compound. Root extracts of I. helenium did not exert any significant anti-inflammatory effect on egg albumin-induced rat paw edema. [...]

Publisher

Journal

Year

Volume

11

Issue

10

Pages

1699-1709

Physical description

Dates

published
1 - 10 - 2013
online
19 - 7 - 2013

Contributors

  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania
  • Agricultural Sciences and Veterinary Medicine University, Iasi, 700490, Romania
  • Oenological Research Center, Romanian Academy, Iasi, 700490, Romania
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania
author
  • National Institute for Chemical Pharmaceutical Research and Development, Bucuresti, 031299, Romania
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania
  • Department of Natural Polymers, “Petru Poni” Institute of Macromolecular Chemistry, Romanian Academy, Iasi, 700487, Romania

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-013-0295-3
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