In vitro bioactivity of Polyurethane/85S Bioglass composite scaffolds

• Authors: Lachezar Radev , Darina Zheleva , Irena Michailova
• Languages of publication: EN

Abstracts

EN

In the present work Polyurethane (PU)/Bioglass (BG) composite materials were synthesized with different content of BG (10 and 20 mol.%) as filler. The 85S Bioglass was synthesized via polystep sol-gel method. The chemical composition of BG is 85SiO2-10CaO-5P2O5 (wt.%). The synthesis of PU was carried out by a two-step polyaddition reaction. The 85S BG was added in situ during the polymerization reaction. In vitro bioactivity of the prepared composites was examined in the presence of 1.5 SBF for 7 days in static conditions. The structure of synthesized PU/BG composites before and after in vitro test was determined by XRD, FTIR and SEM. XRD of the samples before in vitro test proved that the phase of γCa2P2O7 in the PU/20BG is visible. FTIR revealed the presence of urethane bond between OH-(from BG) and NCO groups (from PU). Based on FTIR results after in vitro test in 1.5 SBF solutions, A/B-carbonate containing hydroxyapatite (CO3HA) was formed. XRD proved that HA was formed on the surface of the samples, but Ca2P2O7 does not undergo any changes in the 1.5 SBF solution. SEM depicted the nano-HA agglomerated in spherical particles after immersion in 1.5 SBF for 7 days.

Keywords

EN

Scaffolds; Polyurethane; Bioglass; In vitro bioactivity

• Journal: Open Chemistry
• Year: 2013
• Volume: 11
• Issue: 9
• Pages: 1439-1446

Dates

published

1 - 9 - 2013

online

29 - 6 - 2013

Contributors

author

Lachezar Radev

• Department of Fundamental Chemical Technology, University of Chemical Technology and Metallurgy, Sofia, 1756, Bulgaria,

author

Darina Zheleva

• Textile and Leather Department, University of Chemical Technology and Metallurgy, Sofia, 1756, Bulgaria

author

Irena Michailova

• Department of Silicate Technology, University of Chemical Technology and Metallurgy, Sofia, 1756, Bulgaria

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Identifiers

DOI

10.2478/s11532-013-0273-9