Reaction of barbituric acid with organic azides and phosphonium ylides

• Authors: Iryna Lebedyeva , Sean Sileno , Kunal Patel , Ion Ghiviriga , Peter Steel , Alan Katritzky
• Languages of publication: EN

Abstracts

EN

Amination by organic azides has been carried out to provide aminobarbiturates by fusion of a triazole ring to the 5,6-positions of barbituric acid followed by cleavage and thermal elimination of nitrogen, whereas aza-Wittig reaction gave phosphoranylidene barbituric acid salts. [...]

Keywords

EN

Azide; Aza-Wittig reaction; Pyrimidine; Barbiturate

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2013
• Volume: 11
• Issue: 6
• Pages: 1019-1022

Dates

published

1 - 6 - 2013

online

28 - 3 - 2013

Contributors

author

Iryna Lebedyeva

• Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL, 32611-7200, USA

author

Sean Sileno

• Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL, 32611-7200, USA

author

Kunal Patel

• Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, FL, 32611-7200, USA

author

Ion Ghiviriga

• Department of Chemistry, University of Florida, PO box 117200, Gainesville, FL, 32611, USA

author

Peter Steel

• Chemistry Department, University of Canterbury, Christchurch, 8140, New Zealand

author

Alan Katritzky

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Identifiers

DOI

10.2478/s11532-013-0233-4