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Number of results

Journal

2012 | 10 | 6 | 1760-1765

Article title

Enantioselective inhibition of immobilized acetylcholinesterase in biosensor determination of pesticides

Content

Title variants

Languages of publication

EN

Abstracts

EN
Chiral effects for the inhibition of acetylcholinesterase by organophosphorus pesticides were investigated for insecticide malathion and malaoxon, which is a metabolic product of malathion in living organisms. Studies were carried out using a bienzymatic biosensor with immobilized acetylcholinesterase, choline oxidase, and with Prussian Blue used as a mediator. In both cases the R enantiomers accelerate acetylocholinesterase inhibition. The chiral effect in inhibition was much more pronounced in fast flow measurements than in batch measurements. [...]

Publisher

Journal

Year

Volume

10

Issue

6

Pages

1760-1765

Physical description

Dates

published
1 - 12 - 2012
online
21 - 9 - 2012

Contributors

  • Department of Chemistry, University of Warsaw, 02-093, Warsaw, Poland
  • Department of Chemistry, University of Warsaw, 02-093, Warsaw, Poland
author
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
author
  • Department of Chemistry, University of Warsaw, 02-093, Warsaw, Poland
  • BioMem — IMAGES, University of Perpignan, 66860, Perpignan Cedex, France
  • Department of Chemistry, University of Warsaw, 02-093, Warsaw, Poland

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-012-0101-7
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