PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2011 | 9 | 2 | 213-217
Article title

Analytical performance of a fast multi-element method for titanium and trace elements determination in cosmetics and pharmaceuticals by ICP-AES

Content
Title variants
Languages of publication
EN
Abstracts
EN
A multi-element analytical method based on inductively coupled plasma atomic emission spectrometry (ICP-AES) was developed for trace elements in pharmaceutical tablets and cosmetics. Titanium was also included in the analytes since it is widely used in pharmaceuticals. Critical ICP conditions, like RF incident power, argon gas flow rate and nebulizer sample uptake flow rate were optimized. The most sensitive spectral line of each analyte was selected as optimum for further study. Detection limits in the low µg g−1 range were obtained. Prior to chemical analysis, the samples were decomposed by acid digestion, using various mixtures of HCl, HNO3 and HF. Yttrium was used as a suitable internal standard in order to correct for possible matrix effects. The method was applied to the analysis of six different pharmaceutical products (anti-biotic, anti-inflammatory, anti-hypertensive) in the form of tablets with film coating and also three cosmetic products like hair and face masks.
Publisher

Journal
Year
Volume
9
Issue
2
Pages
213-217
Physical description
Dates
published
1 - 4 - 2011
online
17 - 2 - 2011
Contributors
  • Aristotle University
References
  • [1] L. St-Onge, E. Kwong, M. Sabsabi, E.B. Vadas, Spectrochim. Acta B 57, 1131 (2002) http://dx.doi.org/10.1016/S0584-8547(02)00062-9[Crossref]
  • [2] Y. Luo, J. Zhu, Y. Ma, H. Zhang, Int. J. Pharma. 358, 16 (2008) http://dx.doi.org/10.1016/j.ijpharm.2008.03.028[Crossref]
  • [3] C. Incledon, C. Paquet, A. Johnston, R. Jairam, L. Dass, H. Lam, J. Pharm. Biomed. Anal. 31, 413 (2003) http://dx.doi.org/10.1016/S0731-7085(02)00332-1[Crossref]
  • [4] S. Romero-Torres, J.D. Pérez-Ramos, K.R. Morris, E.R. Grant, J. Pharm. Biomed. Anal. 41, 811 (2006) http://dx.doi.org/10.1016/j.jpba.2006.01.033[Crossref]
  • [5] Y. Sakata, S. Shiraishi, M. Otsuka, Int. J. Pharm. 317, 120 (2006) http://dx.doi.org/10.1016/j.ijpharm.2006.02.058[Crossref]
  • [6] A. Kelko-Levai, I. Varga, K. Zih-Perenyi, A. Lasztity, Spectrochim. Acta B 54, 827 (1999) http://dx.doi.org/10.1016/S0584-8547(99)00036-1[Crossref]
  • [7] European Pharmacopoeia 5.0, 5th edition, Section 2.4.8, Heavy metals (European Directorate of Quality of Medicines, Council of Europe, Strasbourg, France, 2005)
  • [8] G.A. Zachariadis, D.C. Kapsimali, J. Pharm. Biomed. Anal. 41, 1212 (2006) http://dx.doi.org/10.1016/j.jpba.2006.03.003[Crossref]
  • [9] L. Wang, M. Marley, H. Jahansouz, C. Bahnck, J. Pharm. Biomed. Anal. 33, 955 (2003) http://dx.doi.org/10.1016/S0731-7085(03)00364-9[Crossref]
  • [10] N. Lewen, S. Mathew, M. Schenkenberger, T. Raglione, J. Pharm. Biomed. Anal. 35, 739 (2004) http://dx.doi.org/10.1016/j.jpba.2004.02.023[Crossref]
  • [11] A. Lasztity, A. Kelko-Levai, I. Varga, K. Zih-Perenyi, E. Bertalan, Microchem. J. 73, 59 (2002) http://dx.doi.org/10.1016/S0026-265X(02)00052-8[Crossref]
  • [12] J.F. Kauffman, B.J. Westenberger, J. D. Robertson, J. Guthrie, A. Jacobs, S.K. Cummins, Regulatory Toxicol. Pharm. 48, 128 (2007) http://dx.doi.org/10.1016/j.yrtph.2007.03.001[Crossref]
  • [13] J. Jürgens, L. Paama, I. Leito, Accred. Qual. Assur. 12, 593 (2007) http://dx.doi.org/10.1007/s00769-007-0299-9[Crossref]
  • [14] S. Khalil, M.A. El-Ries, J. Pharm. Biomed. Anal. 27, 117 (2002) http://dx.doi.org/10.1016/S0731-7085(01)00521-0[Crossref]
  • [15] G.A. Zachariadis, E. Sahanidou, J. Pharm. Biomed. Anal. 50, 342 (2009) http://dx.doi.org/10.1016/j.jpba.2009.05.003[Crossref]
  • [16] G.A. Zachariadis, C. Vogiatzis, Appl. Spectr. Rev. 45, 220 (2010) http://dx.doi.org/10.1080/05704921003719122[Crossref]
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0149-1
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.