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Journal
2011 | 9 | 1 | 35-40
Article title

Stability-indicating derivative spectrophotometry method for the determination of biapenem in the presence of its degradation products

Content
Title variants
Languages of publication
EN
Abstracts
EN
A first-derivative UV spectrophotometric method, with or without the subtraction technique, was developed for the determination of biapenem in pharmaceutical dosage form in the presence of its degradation products. The method was based on the measurement of first-derivative amplitudes at zero crossing point (λ = 312 nm) and the peak-to-zero technique and validated with regard to linearity, limits of detection and quantitation, selectivity and precision. The observed rate constants for the degradation of biapenem were comparable to those obtained in the stability-indicating HPLC method. [...]
Publisher
Journal
Year
Volume
9
Issue
1
Pages
35-40
Physical description
Dates
published
1 - 2 - 2011
online
16 - 12 - 2010
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-010-0125-9
Identifiers
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