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2010 | 8 | 6 | 1251-1265
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Alkyl methylphosphonic acids, the degradation products of organophosphorous CWA - preparation and direct quantitative GC-FID analysis

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Seven alkyl methylphosphonic acids, products of hydrolytic degradation of organophosphorus chemical warfare agents, were obtained with a high purity (mostly above 98%), with the aim of being applyed as future certified reference materials. Ethyl (EMPA), isopropyl (IMPA), pinacolyl (PMPA), butyl (BUMPA), isobutyl (IBUMPA), cyclohexyl (CHMPA) and 2-ethylhexyl (EHMPA) monoesters of MPA were synthesized and characterized by MS EI, FTIR and NMR (1H, 13C, 31P), TLC, as well as GC and GC-MS after derivatization. The conditions for a direct quantitative GC FID analysis on CP-FFAP CB column of non-derivatized alkyl methylphosphonic acids were developed. This is the first successful attempt of a directed GC analysis of free alkyl phosphonic acids. Their chemical purity was determined and limit of quantification (LOQ) values for some of them were evaluated for the GC-FID method.
Physical description
1 - 12 - 2010
8 - 10 - 2010
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
  • Institute of Industrial Organic Chemistry, 03-236, Warsaw, Poland
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