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Number of results

Journal

2010 | 8 | 6 | 1216-1222

Article title

Comparison of IFCC and NGSP methods for determination of glycated haemoglobin using advanced regression techniques

Content

Title variants

Languages of publication

EN

Abstracts

EN
The objective of this work was a correct statistical comparison of two assay methods for determination of glycated haemoglobin HbA1c. The immunoturbidimetric determination of HbA1c was performed in two ways: using an automatic analyser Hitachi 912, calibrated according to the IFCC reference system (International Federation of Clinical Chemistry and Laboratory Medicine) and using an analyser Advia 1200 and the NGSP reference system (National Glycohaemoglobin Standardization Program). For statistical comparison of these two analytical methods several advanced regression methods were used, which respect random errors of both compared methods. Specifically, Deming regression with and without weights, orthogonal regression, and Passing-Bablok regression were employed. The results demonstrate that the investigated analytical assay methods do not correspond to each other. The summarized results indicate usefulness of better harmonisation of two existing reference systems.

Publisher

Journal

Year

Volume

8

Issue

6

Pages

1216-1222

Physical description

Dates

published
1 - 12 - 2010
online
8 - 10 - 2010

Contributors

  • Department of Chemistry, University of SS. Cyril and Methodius, Trnava, SK-917 01, Slovak Republic
author
  • Department of Chemistry, University of SS. Cyril and Methodius, Trnava, SK-917 01, Slovak Republic
  • Department of Chemistry, University of SS. Cyril and Methodius, Trnava, SK-917 01, Slovak Republic
author
  • Analytical — diagnostic laboratory, Prešov, SK-080 01, Slovak Republic

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-010-0096-x
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