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Number of results

Journal

2010 | 8 | 3 | 639-645

Article title

Synthesis, characterization and antitumor activity of Cu(II), Co(II), Zn(II) and Mn(II) complex compounds with aminothiazole acetate derivative

Content

Title variants

Languages of publication

EN

Abstracts

EN
This paper presents the synthesis of complex compounds of type [M(L1)2], where M(II)= Cu (1), Co (2), Zn (3), L1=2-aminothiazole-4-acetate and [Mn(L1)2(H2O)] (4) using ethyl 2-(2-aminothiazole-4-yl) acetate (L), and characterization by elemental analysis, magnetic susceptibilities, IR, 1H-NMR, UV-Vis spectroscopy and for [Mn(L1)2(H2O)] also by X-ray diffraction. In vitro cytotoxicity studies were performed on human cervix adenocarcinoma, HeLa cells. The antitumor selectivity was assessed using normal human peripheral blood mononuclear cells, PBMC as control. [...]

Keywords

Publisher

Journal

Year

Volume

8

Issue

3

Pages

639-645

Physical description

Dates

published
1 - 6 - 2010
online
25 - 4 - 2010

Contributors

  • Inorganic Chemistry Department, University “Politehnica” of Bucharest, 011061, Bucharest, Romania
  • Department of Biochemistry, University of Belgrade, Faculty of Chemistry, 11000, Belgrade, Serbia
author
  • Inorganic Chemistry Department, University “Politehnica” of Bucharest, 011061, Bucharest, Romania
  • Faculty of Chemistry, Department of Inorganic Chemistry, University of Belgrade, 11000, Belgrade, Serbia
  • C.D. Nenitescu Center of Organic Chemistry of the Romanian Academy, 71141, Bucharest, Romania

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-010-0022-2
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