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Journal
2010 | 8 | 1 | 51-57
Article title

Synthesis and biological screening of octasubstituted-triphenodioxazines and its sulphur analogues with some novel intermediates

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EN
Abstracts
EN
Attempts have been made to prepare for the first time the octasubstituted-triphenodioxazines and triphenodithiazines heterocycles by cyclisation of 3,6-dichloro-2,5-bis(2′,4′,5′-trichloroanilino)-1,4-benzoquinone and condensation. This wasfollowed by cyclisation of substituted 2-aminobenzenethiol respectively with chloranil and bromanil in ethanolic solution of fused sodium acetate in the presence of benzoyl chloride in nitrobenzene. Their structures were confirmed on the basis of their chemical and spectral analyses. Moreover, the biological activity of these compounds was evaluated against the test organisms viz - E.coli, S. aureus, B. subtilis, M.luteus and C. albicans. These compounds synthesized from 2,4,5-trichloroaniline appeared to possess significant antimicrobial activities and an explicit correlation between structure and biological activity was also observed. [...]
Publisher

Journal
Year
Volume
8
Issue
1
Pages
51-57
Physical description
Dates
published
1 - 2 - 2010
online
16 - 2 - 2010
Contributors
author
  • P. G. Research Laboratories, Department of Chemistry, S. D. Govt. College, 305901, Beawar, India
  • P. G. Research Laboratories, Department of Chemistry, S. D. Govt. College, 305901, Beawar, India, pareekcd@yahoo.com
  • P. G. Research Laboratories, Department of Chemistry, S. D. Govt. College, 305901, Beawar, India
  • P. G. Research Laboratories, Department of Chemistry, S. D. Govt. College, 305901, Beawar, India
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-009-0100-5
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