Organic/Inorganic bioactive materials Part III: in vitro bioactivity of gelatin/silicocarnotite hybrids

• Authors: Lachezar Radev , Maria Fernandes , Isabel Salvado , Daniela Kovacheva
• Languages of publication: EN

Abstracts

EN

In this work we present our experimental results on synthesis, structure evolution and in vitro bioactivity assessment of new gelatin/silicocarnotite hybrid materials. The hybrids were obtained by diluting gelatin (G) and silicocarnotite (S) ceramic powder with G:S ratios of 75:25 and 25:75 wt.% in hot (40°C) water. The hybrids were characterized using XRD, FTIR, SEM/EDS and XPS. FTIR depicts that the “red shift” of amide I and COO− could be attributed to the fact that the gelatin prefers to chelate Ca2+ from S. The growth of calcium phosphates on the surface of the hybrids synthesized and then immersed in 1.5 SBF for 3 days was studied by using of FTIR, XRD and SEM/EDS. According to FTIR results, after an immersion of 3 days, A and B-type CO3HA can be observed on the surface. XRD results indicate the presence of hydroxyapatite with well defined crystallinity. SEM/EDS of the precipitated layers show the presence of CO3HA and amorphous calcium phosphate on the surface of samples with different G/S content when immersed in 1.5 SBF. XPS of the G/S hybrid with 25:75 wt.% proved the presence of Ca-deficient hydroxyapatite after an in vitro test for 3 days.

Keywords

EN

Gelatin; Silicocarnotite; Hybrids; In vitro bioactivity

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2009
• Volume: 7
• Issue: 4
• Pages: 721-730

Dates

published

1 - 12 - 2009

online

6 - 10 - 2009

Contributors

author

Lachezar Radev

• Department of Chemical Technology, University of Chemical Technology and Metallurgy, Sofia, 1756, Bulgaria

author

Maria Fernandes

• Department of Ceramic and Glass Engineering and CICECO, University of Aveiro, Aveiro, 3810-193, Portugal

author

Isabel Salvado

• Department of Ceramic and Glass Engineering and CICECO, University of Aveiro, Aveiro, 3810-193, Portugal

author

Daniela Kovacheva

• Institute of General and Inorganic Chemistry, Bulgarian Academy of Sciences, Sofia, 1113, Bulgaria

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Identifiers

DOI

10.2478/s11532-009-0078-z