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Journal
2009 | 7 | 3 | 586-597
Article title

RP-HPLC determination of lipophilicity in series of quinoline derivatives

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Abstracts
EN
In the present paper we describe results on the synthesis and lipophilicity determination of a series of biologically active compounds based on their heterocyclic structure. For synthesis of styrylquinoline-based compounds we applied microwave irradiation and solid phase techniques. The correlation between RP-HPLC retention parameter log k (the logarithm of retention factor k) and log P data calculated in various ways is discussed, as well as, the relationships between the lipophilicity and the chemical structure of the studied compounds. [...]
Publisher

Journal
Year
Volume
7
Issue
3
Pages
586-597
Physical description
Dates
published
1 - 9 - 2009
online
21 - 6 - 2009
Contributors
author
  • Institute of Chemistry, University of Silesia, 40007, Katowice, Poland
author
  • Institute of Chemistry, University of Silesia, 40007, Katowice, Poland
author
  • Institute of Chemistry, University of Silesia, 40007, Katowice, Poland
author
  • Institute of Chemistry, University of Silesia, 40007, Katowice, Poland
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-009-0059-2
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