PL EN


Preferences help
enabled [disable] Abstract
Number of results
Journal
2009 | 7 | 3 | 354-361
Article title

Quick bioanalytical method of quantification and validation of sulbactam in plasma using high performance liquid chromatography

Content
Title variants
Languages of publication
EN
Abstracts
EN
A quick method of quantitative determination of sulbactam in human plasma, using liquid chromatography-UV spectroscopy, has been developed and validated. After derivatization with imidazole, plasma samples were treated by direct deproteinization with acetonitrile as an extraction solvent. After ultracentrifugation, sulbactam extract was directly injected onto the LC column. Chromatographic separation was performed on TSK Gel Super ODS (50 mm × 4.6 mm i.d., 2 μm) using methanol and phosphate buffer with tetrabutylammonium hydroxide solution as a mobile phase. Gradient elution was employed. The method was fully validated according to the United States Food and Drug Administration requirements (linearity, precision, trueness, quantification limit, detection limit, recovery, specificity and stability). The calibration curves were linear within the concentration range of 0.05–4.0 μg mL−1. Good method/system precision and accuracy of the method were demonstrated. [...]
Publisher

Journal
Year
Volume
7
Issue
3
Pages
354-361
Physical description
Dates
published
1 - 9 - 2009
online
21 - 6 - 2009
Contributors
  • Department of Chemistry, Faculty of Science, Tafila Technical University, Tafila, 66110, Jordan, khalidshandi@ttu.edu.jo
References
  • [1] G. Thomas, Medicinal Chemistry, an Introduction (Wiley, UK, 2000) 155
  • [2] K. Abu-Shandi, Eur. J. Sci. Res. 15, 498 (2006)
  • [3] M. Hassan, M. Salim, A. Shakia, J. Jilani, K. Abu-Shandi, N. Najib, Acta Pharm. Sciencia 42, 7 (2000)
  • [4] H. Wang, B. Zhang, Y. Ni, J. Kuti, B. Chen, M. Chen, D. Nicolau, Int. J. of Antimicrob. Agents 30, 452 (2007) http://dx.doi.org/10.1016/j.ijantimicag.2007.06.005[Crossref]
  • [5] H. Bello, E. Solar, C. González, A. Garcia, R. Urrea, R. Zemelman, Diagnos. Microbiol. Infect. Disease 11, 109 (1988) http://dx.doi.org/10.1016/0732-8893(88)90079-X[Crossref]
  • [6] Y. Ishii, J. Alba, S. Kimura, K. Yamaguchi, Diagnos. Microbiol. Infect. Disease 55, 143 (2006) http://dx.doi.org/10.1016/j.diagmicrobio.2006.01.001[Crossref]
  • [7] Y. Ishii, K. Tateda, K. Yamaguchi, JARS, Diagnos. Microbiol. Infect. Disease 60, 177 (2008) http://dx.doi.org/10.1016/j.diagmicrobio.2007.08.006[Crossref]
  • [8] A. Parra, J. Garcia-Villanova, V. Rodenas, M. Gomez, J. Pharm. Biomed. Anal. 12, 653 (1994) http://dx.doi.org/10.1016/0731-7085(93)E0022-F[Crossref]
  • [9] H. Mahgoub, F. Aly, J. Pharm. Biomed. Anal. 17, 1273 (1998) http://dx.doi.org/10.1016/S0731-7085(97)00273-2[Crossref]
  • [10] F.A. Aly, N.A. Alarfaj, A.A. Alwarthan, Anal. Chim. Acta 414, 15 (2000) http://dx.doi.org/10.1016/S0003-2670(00)00800-X[Crossref]
  • [11] L. Puckett, J. Lewis, L. Bachas, S. Daunert, Anal. Biochem. 309, 224 (2002) http://dx.doi.org/10.1016/S0003-2697(02)00304-4[Crossref]
  • [12] G. Pajchel, S. Tyski, 2002, J. Chromatogr. A 979, 315 (2002) http://dx.doi.org/10.1016/S0021-9673(02)01265-7[Crossref]
  • [13] G. Pajchel, K. Pawlowski, S. Tyski, J. Pharm. Biomed. Anal. 29, 75 (2002) http://dx.doi.org/10.1016/S0731-7085(02)00029-8[Crossref]
  • [14] United States Pharmacopoeia XXIII Rev., NF XVIII (American Pharmaceutical Association, Washington, DC, 1995)
  • [15] J. Haginaka, J. Wakai, H. Yasuda, T. Uno, J. Chromatogr. B 341, 115 (1985) http://dx.doi.org/10.1016/S0378-4347(00)84015-3[Crossref]
  • [16] G. Fredj, M. Paillet, F. Aussel, A. Brouard, H. Barreteau, J. Chromatogr. B 383, 218 (1986) http://dx.doi.org/10.1016/S0378-4347(00)83464-7[Crossref]
  • [17] A.J. Shah, M.W. Adlard, J.D. Stride, J. Pharm. Biomed. Anal. 8, 437 (1990) http://dx.doi.org/10.1016/0731-7085(90)80072-W[Crossref]
  • [18] Y. Guillaume, E. Peyrin, C. Guinchard, J. Chromatogr. B 665, 363 (1995) http://dx.doi.org/10.1016/0378-4347(94)00541-C[Crossref]
  • [19] T. Tsou, Y. Huang, C. Lee, A. Lee, H. Wang, S. Chen, J. Sep. Sci. 30(15), 2407 (2007) http://dx.doi.org/10.1002/jssc.200600529[Crossref]
  • [20] I. Aparicio, M.A. Bello, M.l. Callejon, J.C. Jimenez, J. of Chromatogr. Sci. 44(9), 548 (2006) [Crossref]
  • [21] I. Aparicio, M.A. Bello, M.I. Callejon, A. Guiraum, Biomed. Chromatogr. 20(8), 748 (2006) http://dx.doi.org/10.1002/bmc.591[Crossref]
  • [22] E. Fernandez-Varon, C.M. Carceles, A. Espuny, P. Marin, E. Escudero, Am. J. Veter. Res. 65(12), 1658 (2004) http://dx.doi.org/10.2460/ajvr.2004.65.1658[Crossref]
  • [23] R. Koytchev, Y. Ozalp, A. Erenmemisoglu, U. Kunter, Alpan, S. Recep, Arzneimit. Forsch. 54(9a), 634 (2004)
  • [24] A.P. Argekar, S.S. Kunjir, Ind. Drugs 33(7), 352 (1996)
  • [25] M. Qi, R. Chen, R. Cong, P. Wang, J. Liq. Chromatogr. Related Technol. 26(4), 665 (2003) http://dx.doi.org/10.1081/JLC-120017915[Crossref]
  • [26] R.R. Muder, S. Agarwala, A. Mirani, T. Gayowski, R. Venkataramanan, J. Clin. Pharm. 42(6), 644 (2002) http://dx.doi.org/10.1177/00970002042006006[Crossref]
  • [27] A.A. El-Shanawani, Acta Pol. Pharm. 55(1), 9 (1998)
  • [28] J.A. Moody, C.E. Fasching, L.M. Sinn, D.N. Gerding, L.R. Peterson, J. Lab. and Clin. Med. 115(2), 190 (1990)
  • [29] A.J. Shah, M.W. Adlard, J.D. Stride, J. Pharm. Biomed. Anal. 8(5), 437 (1990) http://dx.doi.org/10.1016/0731-7085(90)80072-W[Crossref]
  • [30] L. Snyder, J. Kirkland, J. Glajch, Practical HPLC method development (Wiley, New York, 1997) 21
Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-009-0024-0
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.