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Journal
2008 | 6 | 4 | 562-568
Article title

Synthesis, characterization and antifungal testing of 3,4-dihydropyrimidin-2(1H)-(thio)ones containing boronic acids and boronate esters

Content
Title variants
Languages of publication
EN
Abstracts
EN
The addition of formylphenylboronic acid derivatives to thiourea and ethyl acetoacetate proceeds in the presence of an additional Lewis acid catalyst to give the corresponding 3,4-dihydropyrimidin-2(1H)-(thio)ones (Biginelli products) in moderate yield. Compounds were tested for antifungal activity against pure cultures of Aspergillus niger, Aspergillus flavus, Candida albicans and Saccharomyces cerevisiae but, unfortunately, none showed any appreciable activity. [...]
Publisher

Journal
Year
Volume
6
Issue
4
Pages
562-568
Physical description
Dates
published
1 - 12 - 2008
online
28 - 10 - 2008
Contributors
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
author
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
author
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Biology, Mount Allison University, Sackville, NB, E4L 1G7, Canada
  • Department of Chemistry, University of New Brunswick, Fredericton, NB, E3B 5A3, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada, swestcott@mta.ca
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-008-0064-x
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