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Journal
2007 | 5 | 1 | 118-131
Article title

Copper(II) complexes of the antihypertensive drug nadolol

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Abstracts
EN
The complexation of the non-selective β-blocker nadolol, HL, 1 with copper(II) leads to formation of mono-and dinuclear complexes depending mainly on the metal-to-ligand molar ratio. The mononuclear violet complex CuL2·2Solv, 2, was obtained in a soluble form at metal-to-ligand molar ratio Cu(II): HL ≤ 1: 10 in methanolic or slightly alkaline aqueous solutions. The dinuclear green complex Cu2L2Cl2·H2O, 3 was synthesized at Cu(II): HL ≥ 1: 2 molar ratio in methanolic solutions. The complexes were studied using spectral (UV-Vis, FT-IR, EPR), magnetochemical, thermogravimetric methods and elemental analysis. In the complexes nadolol acts as a monoanionic bidentate ligand coordinated to copper(II) through the NH-and the deprotonated OH-groups of its aminoalcohol fragment. [...]
Keywords
Publisher
Journal
Year
Volume
5
Issue
1
Pages
118-131
Physical description
Dates
published
1 - 3 - 2007
online
1 - 3 - 2007
References
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_s11532-006-0070-9
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