Heteroareno-annelated estranes by triene cyclization

• Authors: Masataka Watanabe , Taisuke Matsumoto , Shuntaro Mataka , Thies Thiemann
• Languages of publication: EN

Abstracts

EN

17-Thienyl-and 17-benzo[b]thienyl-3-hydroxyestra-1,3,5(10),16-tetraenes were synthesized by either sequential or one-pot Suzuki cross-coupling and Wittig olefination reactions. At 160 °C, heteroaryl substituted steroids were observed to undergo thermal intramolecular cyclization to produce E-ring heteroareno-annelated estranes.

Keywords

EN

Steroids; annelation; cyclization; trienes

• Publisher: De Gruyter Open
• Journal: Open Chemistry
• Year: 2006
• Volume: 4
• Issue: 3
• Pages: 375-402

Dates

published

1 - 9 - 2006

online

1 - 9 - 2006

Contributors

author

Masataka Watanabe

• Interdisciplinary Graduate School of Engineering Sciences, Kyushu University, Kasuga-shi, 816-8580, Japan

author

Taisuke Matsumoto

• Institute of Materials Chemistry and Engineering, Kyushu University, Kasuga-shi, 816-8580, Japan

author

Shuntaro Mataka

• Institute of Materials Chemistry and Engineering, Kyushu University, Kasuga-shi, 816-8580, Japan

author

Thies Thiemann

• Institute of Materials Chemistry and Engineering, Kyushu University, Kasuga-shi, 816-8580, Japan

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Identifiers

DOI

10.2478/s11532-006-0016-2