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2015 | 86 | 11 | 518-522
Article title

The Role of Apolipoprotein (A) In Pathogenesis and Clinical Course of Deep Venous Thrombosis

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EN
Abstracts
EN
Deep venous thrombosis is widespread disease, which complications, like: pulmonary embolism and postphlebitis syndrome areimportant social problem. There are many well-known and accurately described risk factors, though in many cases etiology remains unexplained. Further research into causes of deep venous thrombosis seem to be fully justified.The aim of the study was the evaluation of the influence of apolipoprotein (a) serum level in patients with deep venous thrombosis and the changes of its concentration during the treatment.Materials and methods. 26 patients with newly diagnosed deep venous thrombosis (DVT) were enrolled to the study. Diagnosis of DVT was established by use of physical examination and duplex Doppler. Measurements of apolipoprotein (a) and D-dimers serum level were recorded on the following days, starting from the day of the initial diagnosis: 1, 7, 14 and 84.Results. Statistically significant increase of the level of serum apolipoprotein (a) has been found during properly conducted treatment.Conclusions. Alterations of the concentration of serum apoliprotein (a) during the deep venous thrombosis treatment, indicates the involvement of apolipoprotein (a) in pathogenesis of deep venous thrombosis.
Publisher
Year
Volume
86
Issue
11
Pages
518-522
Physical description
Dates
received
20 - 8 - 2014
online
3 - 2 - 2015
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Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_pjs-2014-0092
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