Primary Adenocarcinoma of the Appendix – A Case Report

• Authors: Artur Pasternak , Radosław Pach , Mirosław Szura , Rafał Solecki , Krzysztof A. Tomaszewski , Wojciech Szczepański , Andrzej Matyja , Jan Kulig
• Languages of publication: EN

Abstracts

EN

Primary adenocarcinoma of the vermiform appendix is a rare clinical condition. It usually presents as an acute abdominal process or as a mass in the right lower quadrant. The gross pathologic and microscopic characteristics of this disease are the same as for colon carcinoma and carry a serious prognosis. We report a case of a 64-year old male patient presenting symptoms of acute appendicitis. The patient underwent laparoscopic appendectomy that revealed a severely inflamed appendix. Histopathological examination has shown that it was a poorly differentiated, high grade adenocarcinoma invading the periappendicular fat. According to the histopathological findings, a right hemicolectomy was further advised and performed. Right hemicolectomy is the generally recommended method of treatment for invasive adenocarcinoma of the appendix

Keywords

EN

adenocarcinoma; appendix; laparoscopic appendectomy; right hemicolectomy

• Journal: Polish Journal of Surgery
• Year: 2015
• Volume: 86
• Issue: 7
• Pages: 333-336

Dates

published

1 - 7 - 2014

online

12 - 9 - 2014

received

6 - 6 - 2014

Contributors

author

Artur Pasternak

• Department of General, Oncological and Gastrointestinal Surgery,
• Department of Anatomy

author

Radosław Pach

• Department of General, Oncological and Gastrointestinal Surgery

author

Mirosław Szura

• Department of General, Oncological and Gastrointestinal Surgery

author

Rafał Solecki

• Department of General, Oncological and Gastrointestinal Surgery

author

Krzysztof A. Tomaszewski

• Department of Anatomy

author

Wojciech Szczepański

• Department of Pathology

author

Andrzej Matyja

• Department of General, Oncological and Gastrointestinal Surgery

author

Jan Kulig

• Department of General, Oncological and Gastrointestinal Surgery

References

• 1. Rassu PC, Cassinelli G, Ronzitti F et al.: Primary adenocarcinoma of the appendix. Case report and review of the literature. Minerva Chir 2002; 57: 695-98.
• 2. Berger A: Ein Fall von Krebs des Wurmfortsatzes. Berl Klin Wehnschr 1882; 19: 616-18.
• 3. Ahmed K, Hoque R, El-Tawil S et al.: Adenocarcinoma of the appendix presenting as bilateral ureteric obstruction. World J Surg Oncol 2008; 6: 23 doi: 10.1186/1477-7819-6-23.[Crossref][PubMed][WoS]
• 4. Whitfield CG, Amin SN, Garner JP: Surgical management of primary appendiceal malignancy. C o l o r e c t a l D i s 2 0 1 2 ; 1 4 : 1 5 0 7 - 1 1 doi:10.1111/j.1463-1318.2012.03052.x.[Crossref]
• 5. Walters KC , Paton BL, Schmelzer TS et al.: Treatment of appendiceal adenocarcinoma in the United States: penetration and outcomes of current guidelines. Am Surg 2008; 74: 1066-68.
• 6. Pickhardt PJ, Levy AD, Rohrmann CA Jr et al.: Primary neoplasms of the appendix manifesting as acute appendicitis: CT findings with pathologic comparison. Radiology 2002; 224: 775-81.
• 7. McGory ML, Maggard MA, Kang H et al.: Malignancies of the appendix: beyond case series reports. Dis Colon Rectum 2005; 48: 2264-71.[PubMed][Crossref]
• 8. Köksal AŞ, Kalkan IH, Yildiz H et al.: Direct visualization of an extremely rare malignancy: adenocarcinoma of the appendix. Am J Gastroenterol 2013; 108: 149-50 doi: 10.1038/ajg.2012.339.[WoS][Crossref]
• 9. McCusker ME, Cote TR, Clegg LX et al.: Primary malignant neoplasms of the appendix: a population- based study from the surveillance, epidemiology and end-results program, 1973-1998. Cancer 2002; 94: 3307-12.
• 10. Percy C, Van Holten V, Muir C, editors: International Classification of Diseases for Oncology (ICD-O). 2nd edition. Geneva: World Health Organization, 1990. Available from: URL: http://www. who.int/classifications/icd/en/.
• 11. Fusari M, Sorrentino N, Bottazzi EC et al.: Primary signet ring cell carcinoma of the appendix mimicking acute appendicitis. Acta Radiol 2012; 1: 29 doi: 10.1258/arsr.2012.120017.[Crossref]
• 12. Cirocco WC : Right hemicolectomy remains the treatment of choice for adenocarcinoma of the appendix. Gastrointest Endosc 2005; 61: 791.
• 13. Hata K, Tanaka N, Nomura Y et al.: Early appendiceal adenocarcinoma. A review of the literature with special reference to optimal Surgical procedures. J Gastroenterol 2002; 37: 210-14.
• 14. Nitecki SS , Wolff BG, Schlinkert R et al.: The natural history of surgically treated primary adenocarcinoma of the appendix. Ann Surg 1994; 219: 51-57.
• 15. Ko YH, Jung CK, Oh SN et al.: Primary signet ring cell carcinoma of the appendix: a rare case report and our 18-year experience. World J Gastroenterol 2008; 14: 5763-68.[Crossref][PubMed]
• 16. Culliford AT, Brooks AD, Sharma S et al.: Surgical Debulking and Intraperitoneal Chemotherapy for Established Peritoneal Metastases From Colon and Appendix Cancer. Ann Surg Oncol 2001; 8: 787-95. [Crossref][PubMed]

Identifiers

DOI

10.2478/pjs-2014-0058