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2013 | 85 | 9 | 491-495
Article title

Is Age a Risk Factor of Postoperative Complications in Colorectal Cancer?

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EN
Abstracts
EN
Colorectal cancer is the most common malignant neoplasm in elderly with peak of incidence in 7. and 8. decade of life. Elderly patients with colorectal cancer more often require surgery. Advanced age of patients seems to increase the risk of postoperative complications. The aim of the study was to compare the frequency of early complications in two groups of patients: under 75 and over 75, undergoing elective colorectal cancer surgery. Material and methods. 440 consecutive adult patients subjected to colorectal cancer surgery between 08.2006 to 10.2011 in Oncological Surgery Department, Gdynia Centre of Oncology. Group A (over 75 year-of-life): 109 patients, median 79 and group B (up to 75 year-of-life): 331 patients, median 65. Patients requiring emergency surgery were excluded from the study. Postoperative 30-day mortality, anastomotic leakage, wound infection, bowel obstruction, postoperative respiratory and circulatory insufficiency were among analyzed complications. Results. Symptomatic disease was observed in 81.6% of group A and in 83% of group B. Groups A and B were comparable concerning: BMI, gender, tumor staging, rate of curative and palliative resections, and duration of hospital stay. Accompanying diseases were more common in group A (83% vs 65%; p<0.0002). Early complications occurred in 21.1% of patients from group A and in 19.9% from group B. The rate of reoperation in early perioperative period didn’t differ (6.4% vs 5.7%). Features like: age, gender, additional illnesses, tumor location and staging did not influence the occurrence of perioperative complications. Conclusions. Age itself is not a risk factor for postoperative complications in spite of higher rate of accompanying diseases in elderly.
Publisher
Year
Volume
85
Issue
9
Pages
491-495
Physical description
Dates
published
1 - 09 - 2013
online
15 - 10 - 2013
References
  • 1. Didkowska J, Wojciechowska U, Zatoński W: Krajowy Rejestr Nowotworów. Nowotwory złośliwe w Polsce w 2009 r. Warszawa 2011.
  • 2. Malvezzi M, Arfe A, Bertuccio P et al.: European cancer mortality predictions for the year 2011. Annof Oncology 2011; 22: 947-56.
  • 3. Golfinopoulos V, Pentheroudakis G, Pavlidis: Treatment of colorectal cancer in the elderly: A review of the literatrure. Cancer treatment reviews 2006; 32: 1-8.[PubMed][Crossref]
  • 4. Kotake K, Honjo S, Sugihara K et al.: Changes in colorectal cancer during a 20-year period: an extended report from the multiinstitutional registry of large bowel cancer, Japan. Dis Colon Rectum 2003; 46: 32-46.
  • 5. Endreseth BH, Romunstad P, Myrvold HE et al.: Norwegian Rectal Cancer Group. Rectal cancer treatment of the elderly. Colorectal Dis 2006; 8: 471-79.[Crossref][PubMed]
  • 6. Edna TH, Bjerkeset T: Colorectal cancer in patients over 80 years of age. Hepatogastroenterology 1998; 45: 2142-45.
  • 7. Basili G, Lorenzetti L, Biondi G et al.: Colorectal cancer in the elderly. Is there a role for safe and curative surgery? ANZ J Surg 2008; 78, 6: 466-70.[Crossref]
  • 8. Colorectal Cancer Collaborative Group: Surgery for colorectal cancer in elderly patients: a systematic review. Lancet 2000; 356: 968-74.
  • 9. Nascimbeni R, Di Fabio F, Di Betta E et al.: The changing impact of age on colorectal cancer surgery. A trend analysis. Colorectal Disease 2008; 11: 13-18.[WoS]
  • 10. Ugolini G, Rosati G, Montroni I et al.: Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma. Colorectal Disease 2009; 11: 750-55.[Crossref]
  • 11. Maeda H, Okabayashi T, Ichikawa K et al.: Colorectal cancer surgery in patients older than 80 years of age: experience at one nonteaching hospital in Japan. Am Surg 2011; 11, 77: 1454-59.
  • 12. Khan MR, Bari H, Zafar SN et al.: Impact of age on outcome after colorectal cancer surgery in the elderly- a developing country perspective. BMCSurgery 2011; 11: 17.
  • 13. Marusch F, Koch A, Schmidt U et al.: The impact of the risk factor “age” on the early postoperative results of surgery for colorectal carcinoma and its significance for perioperative management. World J Surg 2005; 29, 8: 1013-21.[PubMed][Crossref]
  • 14. Kristjansson SR , Nesbakken A, Jordhoy MS et al.: Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: a prospective observational cohort study. Crit Rev Oncol Hematol2008; 76, 3: 208-17.[WoS]
  • 15. Janssen-Heijen M, Maas H, Houterman S et al.: Comorbidity in older cancer patients: influence on patient care and outcome. Eur J Cancer 2007; 43: 2179-93.[Crossref]
  • 16. Puig-La CalleJr J, Quayle J et al.: Favorable shortterm and long-term outcome after elective radical rectal cancer resections in patients 75 years of age or older. Dis Colon Rectum 2000; 43, 12: 1704-09.[Crossref]
  • 17. Tan KY , Chen CM, Ng C et al.: Which octogenarians do poorly after major open abdominal surgery in our Asian population? World J Surg 2006; 30, 4: 547-52.[PubMed][Crossref]
  • 18. Ong ES , Alassas M, Dunn KB et al.: Colorectal cancer surgery in the elderly: acceptable morbidity? Am J Surg 2008; 195, 3: 344-48.[Crossref][PubMed]
  • 19. Tan KY , Kawamura Y, Mizokami K et al.: Colorectal surgery in octogenarian patients- outcomes and predictors of morbidity. Int J Colorectal Dis 2009; 24: 185-89.[PubMed][Crossref][WoS]
  • 20. Habr-Gama A, Perez RO , Wynn G et al.: Complete clinical response after neoadjuvantchemoradiation therapy for distal rectal cancer: characterization of clinical and endoscopic findings for standardization. Dis Colon Rectum 2010; 53 (12): 1692-98. [WoS][Crossref]
Document Type
Publication order reference
YADDA identifier
bwmeta1.element.-psjd-doi-10_2478_pjs-2013-0076
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